8-Bromo-cADP-Ribose (8-Br-cADPR) | CAS 151898-26-9

Element: ribose bromo cadpr cadp

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C-S » Chemicals » bromo-cadp-ribose-cadpr-PX64443

Identification

8-Bromo-cADP-Ribose (8-Br-cADPR)

CAS:

151898-26-9

EINECS:

Molecular Formula:

C₁₅H₂₀BrN₅O₁₃P₂

MDL:

MFCD00274402

SMILES:

C1C2C(C(C(O2)N3C4=C(C(=NC=N4)N)N=C3Br)O)OP(=O)(OP(=O)(O1)O)OC5C(C(C(O5)CO)O)O

Synonym:

8-bromocyclic adenosine diphosphate ribose sodium salt ; br-cadp-ribose, br-cadpr ; 8-bromo-cadp-ribose (8-br-cadpr) ; 8-bromo-cyclic adp-ribose ; br-cadp-ribose ; 8-br-cadpr ; br-cadpr ; 8-bromo-cyclic adenosine diphosphate ribose ; 8-bromo-cadp-ribose

Description

8-Bromo-cADP-Ribose (8-Br-cADPR), a cell permeable antagonist of cADPR, has been shown to block cADPR from inducing Ca²⁺ release from sea-urchin-egg homogenates. cADPR has also been observed to regulate calcium release from the sarcoplasmic and endoplasmic reticulum. The antagonist displays the capacity to inhibit arrhythmogenic oscillations of intracellular Ca²⁺ in heart cells. Additionally, this agent has been reported to be an endogenous metabolite of β-NAD⁺.

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Santa Cruz Biotechnology, Inc.

201514

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CAS equal suppliers

8-Bromo-cadp-ribose

Haihang Industry Co., Ltd.

HI4941482

Prices & Availability

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Properties for 8-Bromo-cADP-Ribose (8-Br-cADPR)

Molecular Weight:

620.2 g·mol−1

Solubility:

H₂O: 5 mg/mL

Physical Description:

white lyophilized powder

Safety & Transport Information

Risk Codes:

R36/37/38 - Irritating to eyes, respiratory system and skin

Safety Codes:

S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing

Hazard Symbols:

Storage temperature :

-20°C

Alternative Distributors of [8-Bromo-cADP-Ribose (8-Br-cADPR)]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.

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