Boldine

Boldine, an aporphine alkaloid originally extracted from the leaves of Peumus boldus, is an antioxidant and a potent free-radical scavenger. Experiments on red cells show this compound to be a strong cytoprotective agent in vitro that protects cells against chemically induced hemolytic damage. Additional studies indicate that Boldine may contain anti-inflammatory and antiproliferative properties, and the ability to cause cell cycle arrest at the G₂/M phase.