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Bleomycin Sulfate

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Formula: C55H84N17O21S3.HSO4
CAS: 9041-93-4
search Element: bleomycin sulfate
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Identification

Structural Formula
Bleomycin Sulfate
CAS:
9041-93-4
EINECS:
232-925-2
Molecular Formula:
C55H84N17O21S3.HSO4
MDL:
MFCD00070310
SMILES:
CC1=C(N=C(N=C1N)[C@H](CC(=O)N)NC[C@@H](C(=O)N)N)C(=O)N[C@H]([C@H](C2=CN=CN2)O[C@H]3[C@H]([C@H]([C@@H]([C@@H](O3)CO)O)O)O[C@H]4[C@H]([C@@H]([C@@H]([C@H](O4)CO)O)OC(=O)N)O)C(=O)N[C@H](C)[C@H]([C@H](C)C(=O)N[C@H]([C@@H](C)O)C(=O)NCCC5=NC(=CS5)C6=NC=C(S6)C(=O)NCCC[S+](C)C)O.CC1=C(N=C(N=C1N)[C@H](CC(=O)N)NC[C@@H](C(=O)N)N)C(=O)N[C@H]([C@H](C2=CN=CN2)O[C@H]3[C@H]([C@H]([C@@H]([C@@H](O3)CO)O)O)O[C@H]4[C@H]([C@@H]([C@@H]([C@H](O4)CO)O)OC(=O)N)O)C(=O)N[C@H](C)[C@H]([C@H](C)C(=O)N[C@H]([C@@H](C)O)C(=O)NCCC5=NC(=CS5)C6=NC=C(S6)C(=O)NCCC[S+](C)C)O.[O-]S(=O)(=O)[O-]
Synonym:
blemoycin sulfate ; nsc-125066 ; blocamicina ; blenoxane ; blenoxane, bleo ; blenmycins ; bleomycin sufate ; bleomycin sulfate ; blexane ; bleo


Description

Bleomycin sulfate is the sulfate salt of a complex natural product antibiotic. This compound approximates metals such as Fe(II) which then coordinate dioxygen to generate the active species. This Bleomycin-metal-dioxygen species is capable of inducing oxidative cleavage of the DNA backbone, leading to apoptosis. The species also degrades RNA, and has been reported to display selectivity for RNA over DNA.


Suppliers

H&Z Industry Co.,Ltd
HIC6802720
+
Aea.ltd
A238476
+
Shanghai Chong Da Prostaglandin Fine Chemicals Co., Ltd.
SCDPFC190413328
+
Chemlyte Solutions
CS6121836
+
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI23469384
+
Guangzhou Topwork Chemical Co., Ltd.
GTC12244896
+
Alfa (A Johnson Matthey Company)
A10883264
Xiamen Equation Chemical Co.,Ltd
XECC10885440
+
Quzhou Rundong Chemical Co., Ltd.
QRC11224488
+
Aecochem Corp.
AC4761428
+
CSNpharm, Inc.
CSN10472
Hangzhou Lingrui Chemical Co., Ltd.
HLC11904760
+
Sigma-Aldrich International GmbH
SI10883264
+
Finetech Industry Limited
FIL8503400
+
Carbone Scientific Co., Ltd.
CS9522856
+
Iris Biotech GmbH
LS-1013
+
Xingrui Industry Co., Limited
XIL9863944
+
Capot Chemical Co., Ltd.
18938
+
BOC Sciences
BS4081224
+
Amadis Chemical Company Limited
ACCL10545270
+
Leap Chem Co., Ltd
LC6121836
+
Santa Cruz Biotechnology, Inc.
200134
Dayang Chem (Hangzhou) Co.,Ltd.
DC10544216
+
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Prices & Availability




Data is processed


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Properties for Bleomycin Sulfate

Molecular Weight:
2927.17 g·mol−1
Melting point:
200-204 °C (dec.)
Solubility:
H2O: 20 mg/mL
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Safety & Transport Information

Risk Codes:
R36/37/38 - Irritating to eyes, respiratory system and skin
R40 - Limited evidence of a carcinogenic effect
R46 - May cause inheritable genetic damage
R63 - Possible risk of harm to the unborn child
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
S36/37 - Wear suitable protective clothing and gloves
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S53 - Avoid exposure - obtain special instructions before use
Hazard Symbols:
T, Xi
Hazard symbol T Hazard symbol Xi
Storage temperature :
2-8°C
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Alternative Distributors of [Bleomycin Sulfate]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Inter-Chemical Ltd. | Hangzhou Onicon Chemical Co., Ltd. | Hallochem Pharma Co., Ltd. | Molekula GmbH | Nantong Chem-Tech. (Group) Co., Ltd. | Xingcheng Chempharm Co., Ltd. | Dimysh Trading Company | Shanghai Henghe Pharma-Tech Co., Ltd. | New Dragon Industrial Co., Ltd | Conier Chem & Pharma Ltd | ShangHai Biochempartner Co., Ltd. | Melone Pharmaceutical Co., Ltd. | Shanghai Yingxuan Chempharm Co., Ltd. | Taizhou Bolon Pharmachem Co.,Ltd.. / Bolon Pharm & Chem Co., Ltd. | Shanghai AOKChem Group Limited | Suzhou Rovathin Pharmatech Co., Ltd | Ark Pharm, Inc. | Lanospharma Laboratories Co., Ltd. | Jinan Great Chemical Co., Ltd. | Bichem Lab Co., Ltd. | Hangzhou Holypharm Biotech Co., Ltd. | East Chemical Industry Co., Ltd. | API Vanguard | Discovery Fine Chemicals Limited | Cfm Oskar Tropitzsch GmbH | Aopharm | BOC Sciences | Wuhan Casrn Chemical Co., Ltd | Jinan Haohua Industry Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Wanko Chemical Co., Ltd. | Clearsynth Canada INC.

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