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Bistheonellide A

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Formula: C74H128 O20
CAS: 105304-96-9
search Element: bistheonellide
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Identification

Structural Formula
Bistheonellide A
CAS:
105304-96-9
EINECS:
Molecular Formula:
C74H128 O20
MDL:
SMILES:
CC1CC(CC(O1)CCC(C)C(C(C)C2C(C(CC(C(C(CC3CC=CC(O3)CC(CC=C(C(=O)OC(C(C(CC(C(C(CC4CC=CC(O4)CC(CC=C(C(=O)O2)C)O)OC)C)O)O)C)C(C)C(C(C)CCC5CC(CC(O5)C)OC)O)C)O)OC)C)O)O)C)O)OC
Synonym:
bistheonellidea ; misakinolid a ; misakinolide a ; 8,28,41,42-tetraoxatricyclo[35.3.1.117,21]dotetraconta-5,19,25,39-tetraene-7,27-dione,3,11,13,23,31,33-hexahydroxy-9,29-bis[(1s,2s,3s)-2-hydroxy-1,3-dimethyl-5-[(2s,4r,6s)-tetrahydro-4-methoxy-6-methyl-2h-pyran-2-yl]pentyl]-15,35-dimethoxy-6,10,14,26,30,34-hexamethyl-,(1r,3s,5e,9s,10s,11r,13s,14s,15s,17s,21r,23s,25e,29s,30s,31r,33s,34s,35s,37s)- ; 2,2',3,3'-tetranorswinholide ; 8,28,41,42-tetraoxatricyclo[35.3.1.117,21]dotetracontane, bistheonellide aderiv. ; bistheonellide a ; stereoisomer of3,11,13,23,31,33-hexahydroxy-9,29-bis[2-hydroxy-1,3-dimethyl-5-(tetrahydro-4-methoxy-6-methyl-2h-pyran-2-yl)pentyl]-15,35-dimethoxy-6,10,14,26,30,34-hexamethyl-8,28,41,42-tetraoxatricyclo[35.3.1.117,21]dotetraconta-5,19,25,39-tetraene-7,27-dione ; 8,28,41,42-tetraoxatricyclo[35.3.1.117,21]dotetraconta-5,19,25,39-tetraene-7,27-dione,3,11,13,23,31,33-hexahydroxy-9,29-bis[2-hydroxy-1,3-dimethyl-5-(tetrahydro-4-methoxy-6-methyl-2h-pyran-2-yl)pentyl]-15,35-dimethoxy-6,10,14,26,30,34-hexamethyl-,[1r-[1r*,3s*,5e,9s*[1s*,2s*,3s*,5(2s*,4r*,6s*)],10s*,11r*,13s*,14s*,15s*,17s*,21r*,23s*,25e,29s*[1s*,2s*,3s*,5(2s*,4r*,6s*)],30s*,31r*,33s*,34s*,35s*,37s*]]-


Description

Bistheonellide A is a dimeric marine toxin that can inhibit actin polymerization, as well as cell cycle progression in the G1 phase. Also known as misakinolide A, it can bind simultaneously to two actin subunits with a Kd of 50nM. Research shows that bistheonellide A inhibits G-actin polymerization and depolarizes F-actin in a concentration dependent manner, and that one molecule of bistheonellide A binds to two molecules of G-actin.


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Santa Cruz Biotechnology, Inc.
202081
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Properties for Bistheonellide A

Molecular Weight:
1337.8 g·mol−1
Density:
1.16 g/cm3
Boiling point:
1219.7°C at 760 mmHg
Flash point:
303.6°C
Solubility:
methanol
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Alternative Distributors of [Bistheonellide A]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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Mol File:
-/-
MSDS:
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