(4S,7R,8S,9S,13Z,16S)-4,8-Bis-{[tert-butyl(dimethyl)silyl]oxy}-5,5,7,9,13-pentamethyl-16-[(E)-1-methyl-2-(2-methyl-1,3-thiazol-4-yl)ethenyl]oxocyclohexadec-13-ene-2,6-dione | CAS 189453-35-8

Element: oxocyclohexadec pentamethyl dimethyl ethenyl thiazol methyl methyl butyl dione silyl tert

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C-S » Chemicals » bis-tert-butyl-dimethyl-silyl-oxy-pentamethyl-methyl-methyl-thiazol-ethenyl-oxocyclohexadec-ene-dion

Identification

(4S,7R,8S,9S,13Z,16S)-4,8-Bis-{[tert-butyl(dimethyl)silyl]oxy}-5,5,7,9,13-pentamethyl-16-[(E)-1-methyl-2-(2-methyl-1,3-thiazol-4-yl)ethenyl]oxocyclohexadec-13-ene-2,6-dione

CAS:

189453-35-8

EINECS:

Molecular Formula:

C₃₉H₆₉NO₅SSi₂

MDL:

SMILES:

C[C@H]1CCC/C(=CC[C@H](OC(=O)C[C@@H](C(C(=O)[C@@H](C1O[Si](C)(C)C(C)(C)C)C)(C)C)O[Si](C)(C)C(C)(C)C)/C(=C/C2=CSC(=N2)C)/C)/C

Synonym:

Oxacyclohexadec-13-ene-2,6-dione, 4,8-bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-5,5,7,9,13-pentamethyl-16-[ (1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-, (4S,7R,8S,9S,13Z,16S)-

Description

Intermediary obtained in the synthesis of members of the Epothilone family, polyketide natural products that inhibit cancer cells via a mechanism similar to Paclitaxel. Also found to be effective against Paclitaxel-resistant tumors.

Suppliers

Santa Cruz Biotechnology, Inc.

206960

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CAS equal suppliers

(4S,7R,8S,9S,13Z,16S)-4,8-Bis-{[tert-butyl(dimethyl)silyl]oxy}-5,5,7,9,13-pentamethyl-16-[(E)-1-methyl-2-(2-methyl-1,3-thiazol-4-

Santa Cruz Biotechnology, Inc.

sc-206960

Prices & Availability

Data is processed

Properties for (4S,7R,8S,9S,13Z,16S)-4,8-Bis-{[tert-butyl(dimethyl)silyl]oxy}-5,5,7,9,13-pentamethyl-16-[(E)-1-methyl-2-(2-methyl-1,3-thiazol-4-yl)ethenyl]oxocyclohexadec-13-ene-2,6-dione

Molecular Weight:

720.20 g·mol−1

Solubility:

Soluble in Chloroform, Dichloromethane, Ethanol, Ethyl Acetate, Methanol, Toluene

Safety & Transport Information

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Alternative Distributors of [(4S,7R,8S,9S,13Z,16S)-4,8-Bis-{[tert-butyl(dimethyl)silyl]oxy}-5,5,7,9,13-pentamethyl-16-[(E)-1-methyl-2-(2-methyl-1,3-thiazol-4-yl)ethenyl]oxocyclohexadec-13-ene-2,6-dione]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.

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Mol File:

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MSDS:

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