(3S,6R,7S,12Z,15S,16E)-3,7-Bis-{[tert-butyl(dimethyl)silyl]oxy}-15-hydroxy-4,4,6,8,12,16-hexamethyl-17-(2-methyl-1,3-thiazol-4-yl)-5-oxoheptadeca-12,16-dienoic Acid | CAS 193146-26-8

Element: oxoheptadeca hexamethyl dimethyl dienoic hydroxy thiazol methyl butyl silyl acid tert

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C-S » Chemicals » bis-tert-butyl-dimethyl-silyl-oxy-hydroxy-hexamethyl-methyl-thiazol-oxoheptadeca-dienoic-acid-PX7051

Identification

(3S,6R,7S,12Z,15S,16E)-3,7-Bis-{[tert-butyl(dimethyl)silyl]oxy}-15-hydroxy-4,4,6,8,12,16-hexamethyl-17-(2-methyl-1,3-thiazol-4-yl)-5-oxoheptadeca-12,16-dienoic Acid

CAS:

193146-26-8

EINECS:

Molecular Formula:

C₃₉H₇₁NO₆SSi₂

MDL:

SMILES:

C[C@@H](CCC(C)=C/C[C@H](O)C(C)=CC1=CSC(C)=N1)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](C)C(=O)CC(C)(C)[C@H](CC(O)=O)O[Si](C)(C)C(C)(C)C

Synonym:

Description

Intermediary obtained in the synthesis of members of the Epothilone family, polyketide natural products that inhibit cancer cells via a mechanism similar to Paclitaxel. Also found to be effective against Paclitaxel-resistant tumors. Currently in Phase I of clinical testing.

Suppliers

Santa Cruz Biotechnology, Inc.

206740

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(3S,6R,7S,12Z,15S,16E)-3,7-Bis-{[tert-butyl(dimethyl)silyl]oxy}-15-hydroxy-4,4,6,8,12,16-hexamethyl-17-(2-methyl-1,3-thiazol-4-yl

Santa Cruz Biotechnology, Inc.

sc-206740

Prices & Availability

Data is processed

Properties for (3S,6R,7S,12Z,15S,16E)-3,7-Bis-{[tert-butyl(dimethyl)silyl]oxy}-15-hydroxy-4,4,6,8,12,16-hexamethyl-17-(2-methyl-1,3-thiazol-4-yl)-5-oxoheptadeca-12,16-dienoic Acid

Molecular Weight:

738.22 g·mol−1

Safety & Transport Information

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Alternative Distributors of [(3S,6R,7S,12Z,15S,16E)-3,7-Bis-{[tert-butyl(dimethyl)silyl]oxy}-15-hydroxy-4,4,6,8,12,16-hexamethyl-17-(2-methyl-1,3-thiazol-4-yl)-5-oxoheptadeca-12,16-dienoic Acid]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.

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MSDS:

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