Bimatoprost, free acid | CAS 38344-08-0

Element: bimatoprost acid free

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C-S » Chemicals » bimatoprost-free-acid-PX58318

Identification

Bimatoprost, free acid

CAS:

38344-08-0

EINECS:

Molecular Formula:

C₂₃H₃₂ O₅

MDL:

MFCD00135254

SMILES:

C1[C@@H]([C@@H]([C@H]([C@@H]1O)/C=C/[C@H](CCC2=CC=CC=C2)O)C/C=CCCCC(=O)O)O

Synonym:

5-Heptenoicacid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-pentenyl]cyclopentyl]-,(5Z)- (9CI) ; 5-Heptenoic acid,7-[3,5-dihydroxy-2-(3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl]-, [1R-[1a(Z),2b(1E,3S*),3a,5a]]- ; 17-Phenyl-18,19,20-trinor-PGF2a ; 17-Phenyl-18,19,20-trinorprostaglandin F2a ; Bimatoprost acid ; PhXA 70 ; U 35687 ; 5-Heptenoic acid,7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-,(5Z)-

Description

Bimatoprost, free acid is a metabolically stable analog of PGF_2α and is a potent agonist for the PGF_2α (FP receptor). It binds to the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF_2α. Bimatoprost inhibits PGF_2α binding with a K_i of 1.1 nM at the rat recombinant FP receptor expressed in CHO cells. The isopropyl ester of bimatoprost is slightly better than PGF_2α isopropyl ester in reducing the intraocular pressure in the cat eye with no irritation.

Suppliers

Santa Cruz Biotechnology, Inc.

223818

Dayang Chem (Hangzhou) Co.,Ltd.

DC20468184

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Prices & Availability

Data is processed

Properties for Bimatoprost, free acid

Molecular Weight:

388.5 g·mol−1

Density:

1.219 g/cm3

Melting point:

244.30° C (Predicted)

Boiling point:

597.4°C at 760 mmHg

Flash point:

329.1°C

Solubility:

Soluble in PBS (pH 7.2) (~800 g/ml), ethanol (~100 mg/ml), DMF (~100 mg/ml), and DMSO (~100 mg/ml).

Safety & Transport Information

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Alternative Distributors of [Bimatoprost, free acid]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.

Downloads

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MSDS:

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