(R)-Bicalutamide | CAS 113299-40-4

Element: bicalutamide

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C-S » Chemicals » bicalutamide-PX54953

Identification

(R)-Bicalutamide

CAS:

113299-40-4

EINECS:

Molecular Formula:

C₁₈H₁₄F₄N₂O₄S

MDL:

MFCD00870866

SMILES:

C[C@](O)(CS(=O)(=O)C1=CC=C(F)C=C1)C(=O)NC1=CC=C(C#N)C(=C1)C(F)(F)F

Synonym:

(r)-(-)-bicalutamide ; ici-187555 ; bicalutamide r-isomer ; n-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-flurophenyl)thio]-2-hydroxy-2-methyl-propanamide ; (r)-casodex ; (r)-bicalutamide ; (r)-n-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide ; r-bicalutimide ; (2r)-n-[3-(trifluoromethyl)-4-cyanophenyl]-2-methyl-2-hydroxy-3-(4-fluorophenylsulfonyl)propanamide ; (r)-n-[3-(trifluoromethyl)-4-cyanophenyl]-2-methyl-2-hydroxy-3-(4-fluorophenylsulfonyl)propanamide

Description

(R)-Bicalutamide is an active competitive non-steroidal androgen receptor antagonist with an IC50 of 0.17 μM for MDA 453 cells. (R)-Bicalutamide is the leading antiandrogen, preventing the activation of the androgen receptor and subsequent upregulation of androgen responsive genes by androgenic hormones. In addition, (R)-bicalutamide accelerates the degradation of the androgen receptor.

Suppliers

Santa Cruz Biotechnology, Inc.

219746

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Salsbury Chemicals, Inc.

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Prices & Availability

Data is processed

Properties for (R)-Bicalutamide

Molecular Weight:

430.37 g·mol−1

Melting point:

178-181 °C

Safety & Transport Information

Storage temperature :

-20°C Freezer

Alternative Distributors of [(R)-Bicalutamide]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Jinan Haohua Industry Co., Ltd. | Salsbury Chemicals, Inc.,