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Benserazide·HCl (Ro 4-4602)

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Formula: C10H15N3O5.HCl
CAS: 14919-77-8

Identification

Structural Formula
Benserazide·HCl (Ro 4-4602)
CAS:
14919-77-8
EINECS:
238-991-9
Molecular Formula:
C10H15N3O5.HCl
MDL:
MFCD00078571
SMILES:
C1=CC(=C(C(=C1CNNC(=O)C(CO)N)O)O)O.Cl
Synonym:
benparizde ; benserazide hydrochloride ; spectrum1500137 ; ncgc00093698-03 ; benserazide hcl ; 31796-68-6 ; benserazide hydrochlo ; benserazide hydrochioride ; ro 4-4602/001 ; ro 4-4602


Description

Benserazide·HCl (Ro 4-4602) is a small molecule inhibitor of extracerebral DDC (aromatic L-aminoacid decarboxylase), also known as DOPA decarboxylase. This protein is responsible for decarboxylating L-DOPA to dopamine, 5-hydroxytryptophan to serotonin, and tryptophan to tryptamine. L-DOPA is delivered directly to subjects suffering from a dopaminergic dysfunction such as in Parkinson's disease and dopamine-responsive dystonia - L-DOPA is the natural precursor to dopamine and freely passes the blood brain barrier, while dopamine itself does not. Inhibition of the extracerebral decarboxylation of L-DOPA into dopamine by Benserazide increases the availability of L-DOPA for movement into the brain and subsequent conversion to dopamine. Benserazide·HCl (Ro 4-4602) is an inhibitor of TH and TPH.


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Santa Cruz Biotechnology, Inc.
200723
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Prices & Availability




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Properties for Benserazide·HCl (Ro 4-4602)

Molecular Weight:
293.7 g·mol−1
Melting point:
146 °C
Boiling point:
574.2° C at 760 mmHg (Predicted)
Solubility:
H2O: 10 mg/mL
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Safety & Transport Information

Risk Codes:
R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
Hazard Symbols:
Xi
Hazard symbol Xi
Storage temperature :
-20 °C Freezer
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Alternative Distributors of [Benserazide·HCl (Ro 4-4602)]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Spectrum Chemical Mfg. Corp. | BOC Sciences | Jinan Great Chemical Co., Ltd. | Lanospharma Laboratories Co., Ltd. | Xiamen Topusing Chemical Co., Ltd. | Xiang Ding Chemical International Co., Ltd | New Dragon Industrial Co., Ltd | Watson International Ltd | Goldenchem Co., Ltd. | Hallochem Pharma Co., Ltd. | Shanghai Eagle Chemical Co., Ltd. | Pharmasi Chemicals Co., Ltd. | Luotian Hengxingyuan Chemical Co., Ltd. | Jinan Haohua Industry Co., Ltd. | Hangzhou Pharma & Chem Co. Ltd. | Clearsynth Canada INC. | Suzhou Rovathin Pharmatech Co., Ltd | Shanghai AOKChem Group Limited | Zibo Panxin Pharmaceutical Co., Ltd. | Suzhou Vosun Chemical Co.,Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Jinjiangchem Corporation | East Chemical Industry Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | Sino Rarechem Labs Co. Ltd. | Hubei Yuancheng Saichuang Tech.Co.,Ltd

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