Identification
R-(+)-Baclofen (free base)
Molecular Formula:
C1 0 H1 2 ClNO2
SMILES:
C1=CC(=CC=C1C(CC(=O)O)CN)Cl
Synonym:
(βr)-β-(aminomethyl)-4-chlorobenzenepropanoic acid ; (r)-4-amino-3-(4-chlorophenyl)butyric acid ; l-baclofen ; (r)-4-amino-3-(4-chlorophenyl)butanoic acid ; 4-azanyl-3-(4-chlorophenyl)butanoic acid ; arbaclofen ; r-(+)-baclofen (free base) ; d-baclofen ; stx 209 ; (r)-baclofen
Description
R-(+)-Baclofen (free base) is a selective GABAB receptor agonist. GABAB receptors are metabotropic receptors which produce slow inhibitory signals. By manipulating GABAB receptor activity using Baclofen, a variety of functions are studied including synaptic transmissions and antinociception events.
Suppliers
Santa Cruz Biotechnology, Inc.
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Hangzhou J&H Chemical Co., Ltd.
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Hangzhou MolCore BioPharmatech Co.,Ltd.
MC20860
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Capot Chemical Co., Ltd.
18285
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Excenen Pharmatech Co., Ltd.
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Suzhou Vosun Biotech Co.,Ltd
SVBC842842140
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Zehao Industry Co., Ltd.
ZI722421672
(R)-4-Amino-3-(4-chlorophenyl)butanoic acid
Gihi Chemicals Co., Limited
GCL812732508
(R)-4-Amino-3-(4-chlorophenyl)butanoic acid
Dayang Chem (Hangzhou) Co.,Ltd.
DC933137324
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BLD Pharmatech Ltd
BP541816254
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Chemlyte Solutions
CS541816254
Prices & Availability
Data is processed
Properties
Safety & Transport
Alternative Distributors
Downloads
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Properties for R-(+)-Baclofen (free base)
Molecular Weight:
213.66 g·mol−1
Melting point:
171-174 °C
Solubility:
Soluble in 1M HCl (50mg/ml) or DMSO.
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Hazard Statements
GHS03
Harmful
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, categories 2, 3
Eye irritation, category 2A
Skin sensitization, category 1
Specific target organ toxicity following single exposure, category 3
Not used
with the "skull and crossbones" pictogram
for skin or eye irritation if:
the "corrosion" pictogram also appears
the "health hazard" pictogram is used to indicate respiratory sensitization
Safety & Transport Information
Storage temperature :
Store at RT
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Alternative Distributors of [R-(+)-Baclofen (free base)]
Producers or manufacturers change the product range from time to time.
Currently there are no other manufacturers known.
Element: 
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