Baccatin III | CAS 27548-93-2 | Chemical-Suppliers

Element: baccatin

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C-S » Chemicals » baccatin-iii-PX64474

Identification

Baccatin III

CAS:

27548-93-2

EINECS:

Molecular Formula:

C₃₁H₃₈O₁₁

MDL:

MFCD00153921

SMILES:

CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1O)O)OC(=O)C5=CC=CC=C5)(CO4)OC(=O)C)O)C)OC(=O)C

Synonym:

baccatin iii 98% ; baccatine iii ; 6α,12bβ-diacetoxy-12β-benzoyloxy-1,2aβ,3,4,4a,6,9,10,11,12,12aβ,12b-dodecahydro-4α,9β,11β-trihydroxy-4aα,8,13,13-tetramethyl-7,11α-methano-5h-cyclodeca[3,4]benzo[1,2-b]oxete-5-one ; baccatin iii >=95% (hplc) ; (2ar)-6α,12bβ-diacetoxy-12β-benzoyloxy-1,2aβ,3,4,4a,6,9,10,11,12,12aβ,12b-dodecahydro-4α,9β,11β-trihydroxy-4aα,8,13,13-tetramethyl-7,11α-methano-5h-cyclodeca[3,4]benzo[1,2-b]oxete-5-one ; (1s)-4α,10β-bis(acetoxy)-2α-(benzoyloxy)-5β,20-epoxy-1,7β,13α-trihydroxytaxa-11-ene-9-one ; baccatine iii,95% ; baccatin â…¢ ; nsc 330753 ; baccatin iii

Description

Baccatin III is the precursor to paclitaxel/ taxol. Antileukaemic and antitumor agent isolated from the bark of the Pacific yew tree (Taxus breviofolia). Baccatin III binds to tubules when they are assembled in the cell and stabilizes the polymerized form of tubules so that they remain assembled even under conditions in which microtubules dissociate into tubulin subunits. Baccatin III is also an inducer of apoptosis and shows antitumor properties in vitro

Suppliers

Nantong Xindao Biotech Ltd

NXB6242496

Chengdu Pufeide Biotech. Co., Ltd

CPB7923168

Indofine Chemical Co, Inc.

06-281

Xiamen Equation Chemical Co.,Ltd

XECC7683840

CSNpharm, Inc.

CSN19460

Simagchem Corporation

SC5041512

Xingrui Industry Co., Limited

XIL6962784

Zehao Industry Co., Ltd.

ZI5761728

BOC Sciences

BS288864

Leap Chem Co., Ltd

LC4321296

Santa Cruz Biotechnology, Inc.

204637

Dayang Chem (Hangzhou) Co.,Ltd.

DC7442976

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CAS equal suppliers

Baccatine III

ShangHai Biochempartner Co., Ltd.

BCP09552

Baccatine III

Excenen Pharmatech Co., Ltd.

EX-A832

Baccatine III, 95%

Acros Organics BVBA

AOB6842736

Prices & Availability

Data is processed

Properties for Baccatin III

Molecular Weight:

586.63 g·mol−1

Density:

1.39 g/cm³ (Predicted)

Melting point:

229-234 °C

Boiling point:

713.61° C at 760 mmHg (Predicted)

Solubility:

Soluble in DMSO, 100% ethanol, and methanol.

Safety & Transport Information

Risk Codes:

R22 - Harmful if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
R45 - May cause cancer
R46 - May cause inheritable genetic damage
R48/20/22 - Harmful: danger of serious damage to health by prolonged exposure through inhalation and if swallowed

Safety Codes:

S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S53 - Avoid exposure - obtain special instructions before use

Hazard Classes:

6.1(b)

Hazard Symbols:

Storage temperature :

2-8°C

RID/ADR certification :

1544

Alternative Distributors of [Baccatin III]

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