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5-Azacytidine

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Formula: C8H12N4O5
CAS: 320-67-2
search Element: azacytidine

Identification

Structural Formula
5-Azacytidine
CAS:
320-67-2
EINECS:
206-280-2
Molecular Formula:
C8H12N4O5
MDL:
MFCD00006539
SMILES:
NC1=NC(=O)N(C=N1)[C@@H]1O[C@H](CO)[C@H](O)C1O
Synonym:
5 azc ; 5-ac ; 5-ac-15n4 ; mylosar ; azgr ; u18496 ; 5-azcr ; wr 183027 ; 5-azac ; vidaza


Description

5-Azacytidine is a potent growth inhibitor and a cytotoxic agent. 5-Azacytidine acts as a demethylating agent by inhibiting DNA methyltransferase (Dnmt), forming covalent adducts with cellular DNMT1 depleting enzyme activity. 5-Azacytidine also improves the efficiency of reprogramming of stem cells and induces differentiation of mesenchymal stem cells into cardiomyocytes.


Suppliers

Autech Industry Co.,Limited
AIC3511404
Shandong SanYoung Industry Co., Ltd
SSI4551820
Chemlyte Solutions
CS234702
FUDI Chemical Co. Ltd.
FCC2861144
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI8973588
Shandong Minglang Chemical Co., Ltd
SMC4551820
H&Z Industry Co.,Ltd
HIC2601040
Wuhan PharmChem Co., LTD.
WP325975
JieJie Group Co., Ltd.
JG286858
Guangzhou Topwork Chemical Co., Ltd.
GTC4681872
Xinxiang Aurora Biotechnology Co., Ltd.
XAB5072028
X´ian Taicheng Chem Co., Ltd
XTC3771508
BoomKing Industrial Co.,Limited
BIC4031612
Xiamen Equation Chemical Co.,Ltd
XECC4162080
Sancai Industry Co.,Ltd.
SIC3121248
Fox Chemicals GmbH
FC234702
CSNpharm, Inc.
CSN19354
Wanko Chemical Co., Ltd.
WC312936
Carbone Scientific Co., Ltd.
CS3641092
Acinopeptide Co., Ltd.
A286572
Hefei Hirisun Pharmatech Co., Ltd
HR131339
CM Fine Chemicals
CFC221884
AK Scientific, Inc.
AS247741
DSL Chemicals (Shanghai) Co., Ltd.
C004644
Simagchem Corporation
SC273819
Xingrui Industry Co., Limited
XIL3771508
Capot Chemical Co., Ltd.
14167
Amadis Chemical Company Limited
ACCL4032015
Leap Chem Co., Ltd
LC234702
Santa Cruz Biotechnology, Inc.
221003
Dayang Chem (Hangzhou) Co.,Ltd.
DC4031612
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BLD Pharmatech Ltd
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Prices & Availability




Data is processed


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Properties for 5-Azacytidine

Molecular Weight:
244.2 g·mol−1
Density:
2.08 g/cm3(lit.)
Melting point:
226-232 °C (dec.)(lit.)
Boiling point:
534.5° C (lit.) at 760 mmHg
Solubility:
Soluble in water (50 mg/ml), DMSO (49 mg/ml at 25° C), ethanol (~30 mg/ml), methanol, and DMF (~30 mg/ml).
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Safety & Transport Information

Risk Codes:
R22 - Harmful if swallowed
R45 - May cause cancer
R46 - May cause inheritable genetic damage
Safety Codes:
S22 - Do not breathe dust
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S53 - Avoid exposure - obtain special instructions before use
Hazard Symbols:
T
Hazard symbol T
Storage temperature :
2-8°C
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Alternative Distributors of [5-Azacytidine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

George Uhe Co., Inc. | Zhengzhou Chemprize Biotech Co., Ltd. | Chem-Impex International, Inc. | Hallochem Pharma Co., Ltd. | 3B Scientific Corporation | Xiang Ding Chemical International Co., Ltd | CMS Chemicals Ltd. | Ningbo Pangs Chem Int'l Co., Ltd. | TCI Europe NV | Shamrock(SMK) Bio-Chemical Technology Co., Ltd. | Conier Chem & Pharma Ltd | U-Chemo Holding Co., Limited | Discovery Fine Chemicals Limited | Hangzhou Hysen Pharma Co., Ltd. | Suzhou Rovathin Pharmatech Co., Ltd | Ruiyuan Group Limited | Lanospharma Laboratories Co., Ltd. | Shanghai Hanhong Chemical Co., Ltd. | AOKBIO Co., Ltd. | Jinan Great Chemical Co., Ltd. | 3Way Pharm Inc. | Hangzhou Holypharm Biotech Co., Ltd. | Suzhou Sibian Chemical Technology Co., Ltd. | East Chemical Industry Co., Ltd. | Shanghai Witofly Chemical Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | Hefei Photochem Trading Co., Ltd | Watson International Ltd | Flint Chemical Co., Ltd. | BOC Sciences | Suzhou Bichal Biological Technology Co., Ltd. | Hangzhou Ocean Chemical Co., Ltd. | Changzhou Sunsanta Trading Co., Ltd | Jinan Haohua Industry Co., Ltd. | Finetech Industry Limited | Pfaltz & Bauer, Inc. | Gihi Chemicals Co., Limited | Clearsynth Canada INC. | Amadis Chemical Co., Ltd. | Haihang Industry Co., Ltd.

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