Australine hydrochloride | CAS 118396-02-4

Element: hydrochloride australine

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Identification

Australine hydrochloride

CAS:

118396-02-4

EINECS:

Molecular Formula:

C₈H₁₆ClNO₄

MDL:

SMILES:

C1CN2[C@@H](C([C@@H]([C@H]2C1O)O)O)CO.Cl

Synonym:

7a-epialexine ; australine hydrobromide ; 1h-pyrrolizine-1,2,7-triol, hexahydro-3-(hydroxymethyl)-, (1r,2r,3r,7s,7ar)- ; australine hcl ; hexahydro-3-(hydroxymethyl)-1h-pyrrolizine-1,2,7-triol ; (1r,2r,3r,7s,7ar)-3-hydroxymethyl-1,2,7-trihydroxypyrrolizidine hcl ; australine hydrochloride ; (1r,2r,3r,7s,7ar)-3-hydroxymethyl-1,2,7-trihydroxypyrrolizidine, hydrochloride ; australine, hydrochloride, castanospermum australe

Description

Australine hydrochloride is a polyhydroxylated pyrrolizidine alkaloid that inhibits a-glucosidase, amyloglucosidase, and glucosidase I. Australine hydrochloride appears to be the first glucosidase inhibitor that is active toward glucosidase I but not glucosidase II. Inhibits glycoprotein processing at the gucosidase I step, resulting in the accumulation of glycoproteins containing Glc3Man7-9(GlcNAc)2-oligosaccharides. Does not inhibit a- or b-galactosidase, b-glucosidase, or a- or b-mannosidase.

Suppliers

Santa Cruz Biotechnology, Inc.

202479

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CAS equal suppliers

australine hydrobromide

Indofine Chemical Co, Inc.

06-279

Hexahydro-3-(hydroxymethyl)-1H-pyrrolizine-1,2,7-triol

Leap Chem Co., Ltd

LC583217496

Prices & Availability

Data is processed

Properties for Australine hydrochloride

Molecular Weight:

225.67 g·mol−1

Density:

1.53 ±0.1 g/cm3 (20 °C 760 Torr)

Melting point:

148-149°C (acetone )

Solubility:

Soluble in water (1 mg/ml), ethanol (5 mg/ml), and methanol (5 mg/ml).

Safety & Transport Information

Storage temperature :

0-6°C

Alternative Distributors of [Australine hydrochloride]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Cfm Oskar Tropitzsch GmbH

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Mol File:

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MSDS:

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