Atorvastatin Calcium Salt | CAS 134523-03-8

Element: atorvastatin calcium salt

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C-S » Chemicals » atorvastatin-calcium-salt-PX66421

Identification

Atorvastatin Calcium Salt

CAS:

134523-03-8

EINECS:

Molecular Formula:

(C₃₃H₃₄FN₂O₅)₂Ca

MDL:

MFCD03613598

SMILES:

CC(C)C1=C(C(=C(N1CC[C@H](C[C@H](CC(=O)[O-])O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4.CC(C)C1=C(C(=C(N1CC[C@H](C[C@H](CC(=O)[O-])O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4.[Ca+2]

Synonym:

pd134298-38a ; ym-548 ; sortis ; 3s,5s-atorvastatin ; ci-981 ; atorvastatin ca ; lipitor ; atorvastatin ; atorvastatin c ; tahor

Description

Atorvastatin Calcium Salt is a selective and competitive HMGCR (HMG-CoA reductase) inhibitor, the rate-controlling enzyme of the mevalonate pathway, the metabolic pathway that produces cholesterol and other isoprenoids. Inhibition of HMG-CoA reductase results in a drastic reduction in the production of cholesterol and other isoprenoids. Competitive inhibitors of the reductase are believed to induce the expression of LDL (Low Density Lipoprotein) receptors in the liver, which in turn increases the catabolism of plasma LDL and lowers the plasma concentration of cholesterol.

Suppliers

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Hefei Hirisun Pharmatech Co., Ltd

HR010870

Leap Chem Co., Ltd

LC13504050

Santa Cruz Biotechnology, Inc.

217671

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Wanko Chemical Co., Ltd.

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Prices & Availability

Data is processed

Properties for Atorvastatin Calcium Salt

Molecular Weight:

1155.36 g·mol−1

Melting point:

176-178 °C

Boiling point:

722.2° C at 760 mmHg (Predicted)

Safety & Transport Information

Risk Codes:

R11 - Highly flammable
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
R39/23/24/25 - Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed

Safety Codes:

S16 - Keep away from sources of ignition - No smoking
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
S36/37 - Wear suitable protective clothing and gloves
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S7 - Keep container tightly closed

Hazard Symbols:

Xn, T, F

Storage temperature :

Store at +4 °C

Alternative Distributors of [Atorvastatin Calcium Salt]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified