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N-Arachidonoyl-serotonin

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Formula: C30H42 N2 O2
CAS: 187947-37-1

Identification

Structural Formula
N-Arachidonoyl-serotonin
CAS:
187947-37-1
EINECS:
Molecular Formula:
C30H42 N2 O2
MDL:
MFCD02179189
SMILES:
CCCCC/C=CC/C=CC/C=CC/C=CCCCC(=O)NCCC1=CNC2=C1C=C(C=C2)O
Synonym:
n-arachidonoylserotonin ; n-[2-(5-hydroxy-1h-indol-3-yl)ethyl]-5z,8z,11z,14z-eicosatetraenamide ; 5,8,11,14-eicosatetraenamide,n-[2-(5-hydroxy-1h-indol-3-yl)ethyl]-, (5z,8z,11z,14z)- ; 5,8,11,14-eicosatetraenamide,n-[2-(5-hydroxy-1h-indol-3-yl)ethyl]-, (all-z)- ; aa-5-ht, n-[2-(5-hydroxy-1h-indol-3-yl)ethyl]-(5z,8z,11z,14z)-5,8,11,14-eicosatetraenamide ; n-[2-(5-hydroxy-1h-indol-3-yl)ethyl]-5,8,11,14-eicosatetraenamide ; arachidonylserotonin ; n-arachidonyl-5-hydroxytryptamine ; aa-5-ht ; n-[2-(5-hydroxy-1h-indol-3-yl)ethyl]-(5z,8z,11z,14z)-5,8,11,14-eicosatetraenamide ; arachidonoyl serotonin


Description

N-Arachidonoyl-serotonin is a selective FAAH (fatty acid amid hydrolase) and VR1 (transient receptor potential vanilloid-1, TRPV1) channel inhibitor. TRPV1 is a Capsaicin receptor, which behaves as a non-selective cation channel and are mainly found in the sensory neurons that detect painful stimuli. The compound has been shown to be inactive against cPLA2 and CB1. Rat brain studies suggests that N-Arachidonoyl-serotonin acts as an enhancer of endocannabinoid levels, and increases the levels of anadamide and 2-AG.


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Properties for N-Arachidonoyl-serotonin

Molecular Weight:
462.67 g·mol−1
Density:
1.04 g/mL (Predicted)
Boiling point:
680.49° C at 760 mmHg (Predicted)
Solubility:
Soluble in DMSO (>25 mg/mL), ethanol (15 mg/mL), DMF (30 mg/mL), and PBS (pH 7.2) (~290 µg/mL).
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Safety & Transport Information

Storage temperature :
-20°C
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Alternative Distributors of [N-Arachidonoyl-serotonin]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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Downloads

Mol File:
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MSDS:
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