Apoptosis Activator 2 | CAS 79183-19-0

Element: activator apoptosis

Page Content Identification Properties Suppliers Prices & Availability Get Quick Quote ☰

Identification Properties Suppliers Prices & Availability Get Quick Quote

C-S » Chemicals » apoptosis-activator-PX76816

Identification

Apoptosis Activator 2

CAS:

79183-19-0

EINECS:

Molecular Formula:

C₁₅H₉Cl₂NO₂

MDL:

MFCD00141556

SMILES:

C1=CC=C2C(=C1)C(=O)C(=O)N2CC3=CC(=C(C=C3)Cl)Cl

Synonym:

apoptosis activator 2 ; apoptosis activator ii ; apoptosis activator 2, >=98% ; 1-(3,4-dichlorobenzyl)-1h-indole-2,3-dione ; 1-[(3,4-dichlorophenyl)methyl]-1h-indole-2,3-dione ; 1h-indole-2,3-dione, 1-[(3,4-dichlorophenyl)methyl]-

Description

Apoptosis Activator 2 is a cell-permeable indoledione compound that activates caspases in a cytochrome c-dependent manner and induces apoptosis in tumor cells by promoting the oligomerization of Apaf-1 into the mature apoptosome. Its cytotoxicity is selective towards tumor cells (IC₅₀ < 10 μM for Jurkat, Molt-4, and CCRF-CEM). Apoptosis Activator 2 shows little or no effect on non-tumor cells or cells that are deficient in caspase-3 or Apaf-1. Apoptosis Activator 2 is an activator of caspase-3.

Suppliers

CSNpharm, Inc.

CSN17056

Santa Cruz Biotechnology, Inc.

202956

Dayang Chem (Hangzhou) Co.,Ltd.

DC13025208

Get Quick Quote

CAS equal suppliers

MDK83190

Aea.ltd

A56112

1-(3,4-dichlorobenzyl)indoline-2,3-dione

Hangzhou MolCore BioPharmatech Co.,Ltd.

MC442988

1-(3,4-dichlorobenzyl)indoline-2,3-dione

Capot Chemical Co., Ltd.

33959

1-(3,4-Dichlorobenzyl)-1H-indole-2,3-dione

Leap Chem Co., Ltd

LC378011340

1-(3,4-Dichlorobenzyl)-1H-indole-2,3-dione

Finipharma Ltd

F29405880

Prices & Availability

Data is processed

Properties for Apoptosis Activator 2

Molecular Weight:

306.14 g·mol−1

Density:

1.50 g/cm³ (Predicted)

Melting point:

190.39° C (Predicted)

Boiling point:

470.58° C at 760 mmHg (Predicted)

Solubility:

Soluble in DMSO (5 mg/ml), methanol (5 mg/ml), and ethanol.

Safety & Transport Information

Storage temperature :

Store at RT

Alternative Distributors of [Apoptosis Activator 2]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

BOC Sciences | Excenen Pharmatech Co., Ltd. | Clearsynth Canada INC.

Downloads

Mol File:

-/-

MSDS:

-/-