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(R)-(-)-Apomorphine hydrochloride

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Formula: C17H17 N O2 . Cl H
CAS: 314-19-2

Identification

Structural Formula
(R)-(-)-Apomorphine hydrochloride
CAS:
314-19-2
EINECS:
Molecular Formula:
C17H17 N O2 . Cl H
MDL:
MFCD00069236
SMILES:
CN1CCC2=CC=CC3=C2[C@H]1CC4=C3C(=C(C=C4)O)O.Cl
Synonym:
nsc 11442 ; 4h-dibenzo[de,g]quinoline-10,11-diol,5,6,6a,7-tetrahydro-6-methyl-, hydrochloride, (6ar)- (9ci) ; r-(-)-apomorphinehydrochloride ; apomorphinium chloride ; 6ab-aporphine-10,11-diol, hydrochloride (8ci) ; (-)-apo h cl ; apomorphine hydrochoride ; r(–)-apo ; apomorphinechloride ; apomorphine hcl ; (theta)-id ; apomorphiniumchloride ; 4h-dibenzo[de,g]quinoline-10,11-diol,5,6,6a,7-tetrahydro-6-methyl-, hydrochloride (1:1), (6ar)- ; uprima ; apomorphine hydrochloride ; (-)-apomorphine hydrochloride ; 4h-dibenzo[de,g]quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-,hydrochloride, (r)- ; (r)-id


Description

(R)-(-)-Apomorphine hydrochloride is a prototypical dopamine agonist (pKi values are 6.43, 7.08, 7.59, 8.36, and 7.83 for human recombinant D1, D2L, D3, D4 and D5 receptors respectively). (R)-(-)-Apomorphine hydrochloride, produces biphasic effects on locomotor activity, displays antiparkinsonian, and neuroprotective actions when systemically administered in vivo.


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R-(-)-Apomorphine hydrochloride
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Properties for (R)-(-)-Apomorphine hydrochloride

Molecular Weight:
303.81 g·mol−1
Melting point:
>250°C
Boiling point:
473.4°C at 760 mmHg
Flash point:
268.8°C
Solubility:
Soluble in water (50 mM), and DMSO (100 mM). and mixes with alcohol (1:50).
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Safety & Transport Information

Poison by intravenous and intraperitoneal routes. Mutation data reported. See also APORMORPHINE. When heated to decomposition it emits very toxic fumes of NOx and HCl.
Hazard Classes:
6.1(b)
Storage temperature :
Store at RT
RID/ADR certification :
3249
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Alternative Distributors of [(R)-(-)-Apomorphine hydrochloride]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Clearsynth Canada INC.

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Downloads

Mol File:
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MSDS:
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