Andrographolide | CAS 5508-58-7 | Chemical-Suppliers

Element: andrographolide

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C-S » Chemicals » andrographolide-PX244281

Identification

Andrographolide

CAS:

5508-58-7

EINECS:

226-852-5

Molecular Formula:

C₂₀H₃₀O₅

MDL:

MFCD07778082

SMILES:

C[C@@]12CC[C@H]([C@@]([C@H]1CCC(=C)[C@H]2C/C=C/3[C@@H](COC3=O)O)(C)CO)O

Synonym:

andrographolide ; andrographolide/andrographis paniculata p.e. ; andrographolide (50 mg) ; andrographolid ; 5-alpha,6-alpha,8a-alpha))-t ; andrographalide ; andro ; andrographis ; rhizoma sparganii ; andrographolide(p)

Description

Andrographolide is a bicyclic diterpenoid lactone displaying antiviral, antiinflammatory, antiapoptotic, and antihyperglycemic properties. This chemical is an irreversible antagonist of NF-κB and prevents in vitro T cell activation. Andrographolide displays no effect on IκBa degradation but downregulates iNOS and Mac-1 expressions and ROS production. It has been shown to prevent endotoxin shock in mouse models and is reported to activate PI 3K/Akt pathways. Andrographolide is also an inhibitor of ERK.

Suppliers

Autech Industry Co.,Limited

AIC4051620

Ambeed, Inc.

A108018

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI10354140

Chengdu Pufeide Biotech. Co., Ltd

CPB4951980

Lori Industry Co., Ltd

LI330990

H&Z Industry Co.,Ltd

HIC3001200

Shandong SanYoung Industry Co., Ltd

SSI5252100

Chemlyte Solutions

CS270810

Indofine Chemical Co, Inc.

A-003

Xiamen Equation Chemical Co.,Ltd

XECC4802400

Sancai Industry Co.,Ltd.

SIC3601440

Aecochem Corp.

AC210630

CSNpharm, Inc.

CSN19420

Wanko Chemical Co., Ltd.

WC3601080

Sigma-Aldrich International GmbH

SI4801440

Pharmacore Co., Limited

PL3451035

Acinopeptide Co., Ltd.

A330660

AK Scientific, Inc.

AS285855

Simagchem Corporation

SC315945

Xingrui Industry Co., Limited

XIL4351740

BOC Sciences

BS180540

Leap Chem Co., Ltd

LC270810

Santa Cruz Biotechnology, Inc.

205594

Dayang Chem (Hangzhou) Co.,Ltd.

DC4651860

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CAS equal suppliers

(S,E)-4-Hydroxy-3-(2-((1R,4aS,5R,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylenedecahydronaphthalen-1-yl)ethylidene)dihydrofuran-2(3H)-one

BLD Pharmatech Ltd

BP62928188784

Prices & Availability

Data is processed

Properties for Andrographolide

Molecular Weight:

350.45 g·mol−1

Density:

~1.2 g/cm³ (Predicted)

Melting point:

229-232 °C(lit.)

Boiling point:

~557.3° C at 760 mmHg (Predicted)

Solubility:

Soluble in acetone, methanol, chloroform, ether, water (Partly miscible), and DMSO.

Safety & Transport Information

Risk Codes:

R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin

Safety Codes:

S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing

Hazard Symbols:

Alternative Distributors of [Andrographolide]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

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