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Anastrozole

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Formula: C17H19N5
CAS: 120511-73-1
search Element: anastrozole

Identification

Structural Formula
Anastrozole
CAS:
120511-73-1
EINECS:
Molecular Formula:
C17H19N5
MDL:
MFCD00866298
SMILES:
CC(C)(C#N)C1=CC(=CC(CN2C=NC=N2)=C1)C(C)(C)C#N
Synonym:
zd ; anatrozole ; arimidex ; ici-d-1033 ; anastrozole ; anastrol ; zd-1033 ; anastrazole ; anastrozol ; 2"-[5-(1h-1


Description

Anastrozole is known to inhibit the CYP19 enzyme (aromatase, IC50 = 15 nM) that converts androgens to estrogens. Anastrozole has been seen to reversibly bind to the CYP19 enzyme through competitive inhibition.


Suppliers

H&Z Industry Co.,Ltd
HIC220880
Autech Industry Co.,Limited
AIC2971188
Wuhan PharmChem Co., LTD.
WP275825
Aea.ltd
A77154
Nantong Xindao Biotech Ltd
NXB2861144
Chemlyte Solutions
CS198594
Aozeal Certified Standards (AOCS), Inc.
A0010.00
FUDI Chemical Co. Ltd.
FCC242968
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI7593036
Suan Farma, Inc
SFI165660
Kingreat Chemistry Company Limited
KCCL3741870
Shanghai Worldyang Chemical Co., Ltd.
SWC4071628
Xiamen Equation Chemical Co.,Ltd
XECC3521760
Arakato Development Ltd
AD253759
Aecochem Corp.
AC154462
Sigma-Aldrich International GmbH
SI3521056
scienTEST - bioKEMIX GmbH
S-B2751100
Carbone Scientific Co., Ltd.
CS308924
Pharmacore Co., Limited
PL253759
Hefei Hirisun Pharmatech Co., Ltd
HR011838
AK Scientific, Inc.
AS209627
Capot Chemical Co., Ltd.
16625
BOC Sciences
BS132396
Amadis Chemical Company Limited
ACCL3411705
Leap Chem Co., Ltd
LC198594
Santa Cruz Biotechnology, Inc.
217647
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CAS equal suppliers

Anastrozole-D12
Aozeal Certified Standards (AOCS), Inc.
A0010.15
Anastrozole / arimidex
Gihi Chemicals Co., Limited
GCL11884752
Anastrozole Dimer Impurity
Santa Cruz Biotechnology, Inc.
sc-217648
2,2'-(5-((1H-1,2,4-Triazol-1-yl)methyl)-1,3-phenylene)bis(2-methylpropanenitrile)
Hangzhou MolCore BioPharmatech Co.,Ltd.
CS19826

Prices & Availability




Data is processed


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Properties for Anastrozole

Molecular Weight:
293.37 g·mol−1
Density:
~1.1 g/cm3 (Predicted)
Melting point:
81-82°C
Boiling point:
~469.7° C at 760 mmHg (Predicted)
Solubility:
Soluble in chloroform, methanol, ethanol (59 mg/ml at 25° C), DMSO (59 mg/ml at 25° C), and DMF (~14 mg/ml).
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Hazard Statements

GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
  • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:
R22 - Harmful if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
R60 - May impair fertility
R61 - May cause harm to the unborn child
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S37/39 - Wear suitable gloves and eye/face protection
Hazard Classes:
6.1(b)
Hazard Symbols:
Xi, Xn
Hazard symbol Xn Hazard symbol Xi
Storage temperature :
Store at RT
RID/ADR certification :
3249
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Alternative Distributors of [Anastrozole]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Conier Chem & Pharma Ltd | Finetech Industry Limited | BOC Sciences | Inter-Chemical Ltd. | Jinan Great Chemical Co., Ltd. | TCS INDUSTRY LTD. | Lanospharma Laboratories Co., Ltd. | Evershine Chemical Co.,Ltd. | Kinfon Pharmaceutical and Chemical Service Co., Ltd. | Xiang Ding Chemical International Co., Ltd | New Dragon Industrial Co., Ltd | Trademax Phamaceuticals & Chemicals Co., Ltd. | Zhejiang Xianju Greeleaf Pharmaceutical Factory | Watson International Ltd | 3B Scientific Corporation | BTX Global Pharmaceuticals, Inc. | Shanxi Jinjin Chemical Co., Ltd. | Aryl S.A. | Synfine Research Inc. | Auspure Biotechnology Co., Ltd. | Hallochem Pharma Co., Ltd. | Heta Pharm & Chem Co., Ltd. | Shanghai Eagle Chemical Co., Ltd. | Hangzhou Think Chemical Co., Ltd. | Hangzhou Keriopharm. Chem. Co., Ltd. | scienTEST | Pharmasi Chemicals Co., Ltd. | Hangzhou FST Pharmaceutical Co., Ltd. | Hangzhou Hysen Pharma Co., Ltd. | Afine Chemicals Limited | Beijing Lunarsun Pharmaceutical Co. Ltd. | Qichun QiLong Chemical Co., Ltd. | Jinan Haohua Industry Co., Ltd. | Nantong Chem-Tech. (Group) Co., Ltd. | ChengDu KaiXin Technology Development Co., Ltd. | Jiangsu Honghui Pharmaceutical Co., Ltd. | Taizhou Huading Chemical Co., Ltd. | Duheng Bio-tech Co., Ltd. | Zhejiang Esun Chemical Co., Ltd. | Borun Chemical Co., Ltd. | China Yangzhou Wandong Medical Co., Ltd. | Clearsynth Canada INC. | Suzhou Rovathin Pharmatech Co., Ltd | Shanghai Henghe Pharma-Tech Co., Ltd. | Shanghai AOKChem Group Limited | Zibo Panxin Pharmaceutical Co., Ltd. | Long Island Pharmaceutical & Chemical Co. Ltd. | Shanghai Richem International Co., Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd. | Suzhou Vosun Chemical Co.,Ltd. | Haihang Industry Co., Ltd. | Ningbo Haishu Hobid Imp & Exp Co., Ltd. | Andy Chemicals CO., Ltd. | Shanghai Boyle Chemical Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Bichem Lab Co., Ltd. | Hangzhou Holypharm Biotech Co., Ltd. | East Chemical Industry Co., Ltd. | Shanghai Witofly Chemical Co., Ltd. | Aopharm | Kairer Chengdu Pharmaceutical Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | Benro Internatinal Co., Linc | Grandachem Ltd. | API Vanguard | Hubei Yuancheng Saichuang Tech.Co.,Ltd | All Right Chemical Co., Ltd. | Varnor Chemical Co.,Limited | Zhuhai Jiacheng Bio-Tech Co., Ltd.

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