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Amprenavir

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Formula: C25H35N3O6S
CAS: 161814-49-9
search Element: amprenavir
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Identification

Structural Formula
Amprenavir
CAS:
161814-49-9
EINECS:
Molecular Formula:
C25H35N3O6S
MDL:
MFCD00934214
SMILES:
CC(C)(C)N(C[C@@H](O)[C@H](CC1=CC=CC=C1)NC(=O)O[C@H]1CCOC1)S(=O)(=O)C1=CC=C(N)C=C1
Synonym:
vx 478 ; prozei ; 141w94, kvx-478, agenerase, prozei, ; angenerase ; agenerase ; amprenavir(kvx-478) ; kvx-478 ; amprenavir ; 141w94 ; amprenavir(agenerase)


Description

Amprenavir is a human immunodeficiency virus (HIV) protease inhibitor with IC50 of 14.6 ± 12.5 ng/ml for wild-type HIV isolates. Like all HIV protease inhibitors, amprenavir interrupts the maturation phase of the HIV replicative cycle by forming an inhibitor-enzyme complex, which prevents HIV protease from binding with its normal substrates. This compound has an enzyme inhibition constant (Ki = 0.6 nM) that falls within the Ki range of the other protease inhibitors. Amprenavir is an inhibitor of HIV-1 Protease.


Suppliers

Aozeal Certified Standards (AOCS), Inc.
A0019.00
+
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI6902760
+
Aea.ltd
A70140
+
Chemlyte Solutions
CS180540
+
Alpha Biopharmaceuticals Co., Ltd.
AB3401020
+
Xiamen Equation Chemical Co.,Ltd
XECC3201600
+
CSNpharm, Inc.
CSN16717
Hangzhou Lingrui Chemical Co., Ltd.
HLC3501400
+
scienTEST - bioKEMIX GmbH
S-B2501000
+
AK Scientific, Inc.
AS190570
+
Leap Chem Co., Ltd
LC180540
+
Santa Cruz Biotechnology, Inc.
207287
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Prices & Availability




Data is processed


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Properties for Amprenavir

Molecular Weight:
505.63 g·mol−1
Density:
~1.3 g/cm3 (Predicted)
Melting point:
72-74 °C
Solubility:
Soluble in DMSO (16 mg/ml at 25° C), chloroform, dichloromethane, ethanol (101 mg/ml at 25° C), and water (partly).
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Safety & Transport Information

Storage temperature :
-20 °C Freezer
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Alternative Distributors of [Amprenavir]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

BOC Sciences | Wuxi Mizat Chemical Technology Co., Ltd. | Jinan Great Chemical Co., Ltd. | Apichem Chemical Technology Co., Ltd. | Evershine Chemical Co.,Ltd. | 3B Scientific Corporation | scienTEST | Jinan Haohua Industry Co., Ltd. | Clearsynth Canada INC. | Shanghai AOKChem Group Limited | Chengdu Qiaofeng Technological Development Co., Ltd. | Haihang Industry Co., Ltd. | AOKBIO Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Suzhou Sibian Chemical Technology Co., Ltd. | East Chemical Industry Co., Ltd. | Wanko Chemical Co., Ltd.

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Downloads

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MSDS:
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