AMPA | CAS 74341-63-2 | Chemical-Suppliers

Element: ampa

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C-S » Chemicals » ampa-PX66154

Identification

AMPA

CAS:

74341-63-2

EINECS:

Molecular Formula:

C₇H₁₀N₂O₄

MDL:

MFCD00213388

SMILES:

CC1=C(C(=O)NO1)CC(C(=O)O)N

Synonym:

(r,s)-a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid ; 3-(3-hydroxy-5-methylisoxazol-4-yl)-dl-alanine ; ampa ; 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propanoic acid ; (+-)-a-amino-3-hydroxy-5-methyl-isoxazol e-4-propio ; d,l-α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid ; (rs)-ampa ; γ-amino-3-hydroxy-5-methylisoxazole-4-propionic Î‘cid ; ampa hydrate ; (+/-)-amino-3-hydroxy-5-methylisoxazolepropionic acid

Description

AMPA is a specific agonist of the GluR (AMPA receptor), an ionotropic receptor that recognizes glutamate as its natural substrate. The AMPA receptor is described to mediate a large amount of excitatory neurotransmission processes, and agonism at the AMPA receptor produces neuronal excitation and current induction. AMPA is employed as a tool to identify participation of the AMPA receptor in a neuronal response and to distinguish between activity at the AMPA receptor and at the glutamate-recognizing NMDA and Kainic acid receptors.