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Amitriptyline Hydrochloride

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Formula: C20H23N.HCl
CAS: 549-18-8
search Element: amitriptyline hydrochloride
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Identification

Structural Formula
Amitriptyline Hydrochloride
CAS:
549-18-8
EINECS:
208-964-6
Molecular Formula:
C20H23N.HCl
MDL:
MFCD00012537
SMILES:
CN(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31.Cl
Synonym:
normaln ; etrafon ; amitid ; deprex ; rantoron ; domical ; amiplin ; triavil ; endep ; saroten


Description

Amitriptyline Hydrochloride is an antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.


Suppliers

H&Z Industry Co.,Ltd
HIC10804320
+
Shandong SanYoung Industry Co., Ltd
SSI18907560
+
Ambeed, Inc.
A315453
+
Aozeal Certified Standards (AOCS), Inc.
A0032.00
+
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI372614904
+
European Manufacturers Assoc. Inc.
EMA18367344
Jai Radhe Sales
JRS8103240
+
AXO Industry SA
AIS8103240
+
Xiamen Equation Chemical Co.,Ltd
XECC17288640
+
Hainan Zhongxin Chemical Co., Ltd.
HZC18367344
+
Aecochem Corp.
AC7562268
+
Hangzhou Keying Chem Co., Ltd.
HKC16206480
+
Wanko Chemical Co., Ltd.
WC12963888
Sigma-Aldrich International GmbH
SI17285184
+
scienTEST - bioKEMIX GmbH
S-B13505400
+
Hefei Hirisun Pharmatech Co., Ltd
HHP17827128
+
AK Scientific, Inc.
AS10263078
+
Leap Chem Co., Ltd
LC9722916
+
Santa Cruz Biotechnology, Inc.
210801
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Alfa (A Johnson Matthey Company)
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Gihi Chemicals Co., Limited
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Capot Chemical Co., Ltd.
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Prices & Availability




Data is processed


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Properties for Amitriptyline Hydrochloride

Molecular Weight:
313.86 g·mol−1
Melting point:
196-197 °C
Flash point:
11 °C
Solubility:
H2O: soluble
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Hazard Statements

GHS06

GHS06
Toxic
  • Acute toxicity (oral, dermal, inhalation), categories 1, 2, 3
GHS08

GHS08
Health hazard
  • Respiratory sensitization, category 1
  • Germ cell mutagenicity, categories 1A, 1B, 2
  • Carcinogenicity, categories 1A, 1B, 2
  • Reproductive toxicity, categories 1A, 1B, 2
  • Specific target organ toxicity following single exposure, categories 1, 2
  • Specific target organ toxicity following repeated exposure, categories 1, 2
  • Aspiration hazard, categories 1, 2
GHS09

GHS09
Environmental hazard
  • Acute hazards to the aquatic environment, category 1
  • Chronic hazards to the aquatic environment, categories 1, 2
  • Environmental toxicity, categories 1, 2

Safety & Transport Information

Risk Codes:
R11 - Highly flammable
R22 - Harmful if swallowed
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed
R36 - Irritating to eyes
R36/37/38 - Irritating to eyes, respiratory system and skin
R39/23/24/25 - Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed
R42/43 - May cause sensitization by inhalation and skin contact
R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
R63 - Possible risk of harm to the unborn child
Safety Codes:
S16 - Keep away from sources of ignition - No smoking
S22 - Do not breathe dust
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37 - Wear suitable protective clothing and gloves
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S60 - This material and its container must be disposed of as hazardous waste
S61 - Avoid release to the environment. Refer to special instructions/safety data sheet
S7 - Keep container tightly closed
Hazard Classes:
6.1(b)
Hazard Symbols:
T, F, N, Xn
Hazard symbol T Hazard symbol N Hazard symbol F Hazard symbol Xn
Storage temperature :
2-8°C
RID/ADR certification :
UN 2811 6.1 / PG 3
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Alternative Distributors of [Amitriptyline Hydrochloride]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Spectrum Chemical Mfg. Corp. | ABCR GmbH & Co. KG | Watson International Ltd | Nantong Chem-Tech. (Group) Co., Ltd. | TCI Europe NV | CCS. CHEM. Co., Ltd. | Shanghai AOKChem Group Limited | Suchem Pharma Co., Ltd. | Kinfon Pharmaceutical and Chemical Service Co., Ltd. | Jinan Great Chemical Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | API Vanguard | Cfm Oskar Tropitzsch GmbH | BOC Sciences | Jinan Haohua Industry Co., Ltd. | Finetech Industry Limited | Suzhou Vosun Chemical Co.,Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Clearsynth Canada INC. | scienTEST | Haihang Industry Co., Ltd.

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