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4-Aminopyridine

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Formula: C5H6N2
CAS: 504-24-5
search Element: aminopyridine

Identification

Structural Formula
4-Aminopyridine
CAS:
504-24-5
EINECS:
207-987-9
Molecular Formula:
C5H6N2
MDL:
MFCD00006439
SMILES:
C1=CN=CC=C1N
Synonym:
prc 1237 ; ampyra ; 4-ap ; 4apy ; vmi10-3 ; avitrol ; mi-w-3 ; el 970 ; vmi 10-3 ; neurelan


Description

4-Aminopyridine (4-AP) is a nonselective K+ channel blocker that has been used to characterize and study the blockage of K+ channels. Studies show that 4-AP binds from the cytoplasmic side of the cell membrane. Research suggests that 4-AP extends the potentials of unmyelinated and demyelinated fibers, facilitates conduction in fibers blocked by demyelination, and can induce glutamate and neurotransmitter γ-aminobutyric acid (GABA) release.


Suppliers

H&Z Industry Co.,Ltd
HIC3001200
Krada CPS Industry S.L
KCIS3301650
Wuhan PharmChem Co., LTD.
WP3751125
Minascent Technologies GmbH
MT4051215
Chemlyte Solutions
CS270810
Autech Industry Co.,Limited
AIC4051620
FUDI Chemical Co. Ltd.
FCC3301320
Cangzhou Goldlion Chemicals Co., Ltd.
CGC5552220
Jubilant Life Science Ltd.
6
DKSH International AG
DIA3151260
INNOCHEM
I120240
CellMark AB
CA165495
IBIS Chemie International
ICI3751500
Biesterfeld Spezialchemie GmbH
BS4501350
General Intermediates of Canada, Inc.
GIOC5552775
BoomKing Industrial Co.,Limited
BIC4651860
Shanghai Worldyang Chemical Co., Ltd.
SWC5552220
Evonik ( formerly Wilshire Technologies, Inc. )
E7202880
Hainan Zhongxin Chemical Co., Ltd.
HZC5102040
Daming Changda Co., Ltd.
LLB00254
Aecochem Corp.
AC210630
Merck Schuchardt OHG
MSO3001200
Wanko Chemical Co., Ltd.
WC3601080
Sigma-Aldrich International GmbH
SI4801440
scienTEST - bioKEMIX GmbH
S-B3751500
Hangzhou Ocean Chemical Co., Ltd.
HOC4951980
Carbone Scientific Co., Ltd.
CS4201260
CM Fine Chemicals
CFC2551020
AK Scientific, Inc.
AS285855
DSL Chemicals (Shanghai) Co., Ltd.
DC5102040
Xingrui Industry Co., Limited
XIL4351740
Capot Chemical Co., Ltd.
1281
Leap Chem Co., Ltd
LC270810
Santa Cruz Biotechnology, Inc.
202421
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Prices & Availability




Data is processed


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Properties for 4-Aminopyridine

Molecular Weight:
94.11 g·mol−1
Density:
1.26
Melting point:
157 °C
Boiling point:
273 °C(lit.)
Flash point:
156 °C
Solubility:
Soluble in water (50 mg/ml), 100% ethanol, methanol (slightly), alcohol, and DMSO (100 mM).
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Safety & Transport Information

Risk Codes:
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed
R28 - Very toxic if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
Safety Codes:
S1 - Keep locked up
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S37/39 - Wear suitable gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S60 - This material and its container must be disposed of as hazardous waste
S61 - Avoid release to the environment. Refer to special instructions/safety data sheet
Hazard Classes:
6.1
Hazard Symbols:
T+, N, T, Xi
Hazard symbol T Hazard symbol N Hazard symbol Xi Hazard symbol T+
Storage temperature :
0-6°C
RID/ADR certification :
UN 2671 6.1 / PG 2
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Alternative Distributors of [4-Aminopyridine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Shanghai Jinglan Chemical Co., Ltd. | Spectrum Chemical Mfg. Corp. | Finetech Industry Limited | ABCR GmbH & Co. KG | Pfaltz & Bauer, Inc. | Junwee Chemical Co., Ltd. | Jinan Great Chemical Co., Ltd. | Hisyntech Corporation Limited | Rongkang Industry Co.,Ltd - (NSTU Chemicals Hanggzhou Co.,) | Xiang Ding Chemical International Co., Ltd | Trademax Phamaceuticals & Chemicals Co., Ltd. | Watson International Ltd | 3B Scientific Corporation | Kunshan Huaxin Daily Chemicals Co., Ltd. | Hebei Daguan Chemical Technology Co., Ltd. | Ruiyi Medical Co., Ltd. | TCI Europe NV | Beijing Wisdom Chemicals Co., Ltd | Ubichem PLC | Zhejiang Jiangbei Pharmaceutical Co., Ltd. | JVR Fine Chemie Pvt. Ltd. | Shanghai Jiayi Fine Chemical Co., Ltd. | Molekula GmbH | Nowa Pharmaceuticals Co.,Ltd. | Hallochem Pharma Co., Ltd. | Yongyi Chemicals Group Co., Ltd. | Hongda Group Limited | scienTEST | Pharmasi Chemicals Co., Ltd. | Shanghai Hanhong Chemical Co., Ltd. | Tangshan Wisdom Trading Co., Ltd. | Intatrade Chemicals GmbH | Jinan Haohua Industry Co., Ltd. | Vesino Industrial Co., Ltd. | Shenzhen Xing Jia Feng Since and Technology Development Co., Ltd. | Nanjing FineTech Chemical Co., Ltd. | Suzhou Rovathin Pharmatech Co., Ltd | Jinan TaiFei Science & Technology Co., Ltd. | Nantong Qihai Chemicals Co., Ltd. | Shanghai AOKChem Group Limited | Chengdu Qiaofeng Technological Development Co., Ltd. | Hangzhou Sida Organic Chemical Co., Ltd. | Suzhou Vosun Chemical Co.,Ltd. | Haihang Industry Co., Ltd. | AOKBIO Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Bichem Lab Co., Ltd. | Aakash Chemicals & Dye-Stuffs, Inc. | East Chemical Industry Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | Chemwill Asia Co.,Limited | Aspirebio | Pangea Chemicals | Medilink Pharmachem

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