Aminoglutethimide | CAS 125-84-8

Element: aminoglutethimide

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C-S » Chemicals » aminoglutethimide-PX69800

Identification

Aminoglutethimide

CAS:

125-84-8

EINECS:

204-756-4

Molecular Formula:

C₁₃H₁₆N₂O₂

MDL:

MFCD00010122

SMILES:

CCC1(CCC(=O)NC1=O)C1=CC=C(N)C=C1

Synonym:

cytadren ; akos ncg1-0032 ; ba-16038 ; timtec-bb sbb000711 ; dl-aminoglutethimide ; aminoglutethamide ; aminoglutethimide ; nsc-330915 ; elipten ; orimeten

Description

Aminoglutethimide has been shown to inhibit human placental CYP19 (aromatase) in vitro. In ovine adrenocortical cells, aminoglutethimide has been shown to inhibit ACTH receptor mRNA expression in a time-dependent manner in vitro. It significantly suppresses baseline ACTH-R mRNA expression and steriod secretion in a dose-dependent manner in vitro in the human NCI-h295 adrenocortical carcinoma cell line. In vivo, Aminoglutethimide is known to accelerate its own metabolism and the metabolism of synthetic dexamethasone and glucocorticoid.

Suppliers

JieJie Group Co., Ltd.

JG3741122

X´ian Taicheng Chem Co., Ltd

XTC4931972

Xiamen Equation Chemical Co.,Ltd

XECC5442720

Sancai Industry Co.,Ltd.

SIC4081632

Sigma-Aldrich International GmbH

SI5441632

Acinopeptide Co., Ltd.

A374748

AK Scientific, Inc.

AS323969

Leap Chem Co., Ltd

LC306918

Santa Cruz Biotechnology, Inc.

207280

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CAS equal suppliers

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MC436181

DL-Aminoglutethimide

Bachem AG

Q-1020.0005

DL-Aminoglutethimide, 99%

Alfa (A Johnson Matthey Company)

A8002400

3-(4-Aminophenyl)-3-ethyl-2,6-piperidinedione

Hangzhou J&H Chemical Co., Ltd.

HJC697527900

3-(4-Aminophenyl)-3-ethylpiperidine-2,6-dione

Salsbury Chemicals, Inc.

SC540016200

2,6-Piperidinedione, 3-(4-aminophenyl)-3-ethyl-

Angene International Limited

AGN-PC-0JK651

Prices & Availability

Data is processed

Properties for Aminoglutethimide

Molecular Weight:

232.28 g·mol−1

Density:

~1.2 g/cm³ (Predicted)

Melting point:

152-154 °C(lit.)

Boiling point:

~457.4° C at 760 mmHg (Predicted)

Solubility:

H₂O: 0.2 mg/mL, slightly soluble

Hazard Statements

GHS03
Harmful

Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, categories 2, 3
Eye irritation, category 2A
Skin sensitization, category 1
Specific target organ toxicity following single exposure, category 3
- Respiratory tract irritation
- Narcotic effects

Not used

with the "skull and crossbones" pictogram
for skin or eye irritation if:
the "corrosion" pictogram also appears
the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:

R36/37/38 - Irritating to eyes, respiratory system and skin

Safety Codes:

S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing

Hazard Classes:

6.1(b)

Hazard Symbols:

Storage temperature :

2-8°C

RID/ADR certification :

3249

Alternative Distributors of [Aminoglutethimide]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

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