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1-Aminocyclopropane-1-Carboxylic Acid

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Formula: C4H7NO2
CAS: 22059-21-8
search Element: aminocyclopropane carboxylic acid
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Identification

Structural Formula
1-Aminocyclopropane-1-Carboxylic Acid
CAS:
22059-21-8
EINECS:
Molecular Formula:
C4H7NO2
MDL:
MFCD00009944
SMILES:
C1CC1(C(=O)O)N
Synonym:
nsc 98430 ; 1-aminocyclopropanecarbox... ; acc ; ac3c ; 1,1-accp ; h-acpc-oh ; 1-amino-1-carboxycyclopropane ; carboxycyclopropylamine ; h-(1)nhcpropn-oh ; h-acc-oh.hcl


Description

1-Aminocyclopropane-1-carboxylic Acid is a small molecule agonist at the glycine modulatory site of the NMDA receptor. Described to mimic the effects of glycine at the NMDAR, 1-Aminocyclopropane-1-carboxylic Acid competitively inhibits binding of [3H]glycine and enhances the binding of [3H]MK-801 to NMDAR-coupled cation channels similarly to glycine (though with less efficacy). 1-Aminocyclopropane-1-carboxylic Acid is shown to block convulsions and death produced by NMDA exposure, significantly reducing seizure induction and cell death of NMDA-treated hippocampal neurons. 1-Aminocyclopropane-1-carboxylic Acid is produced endogenously in the tomato and other higher plants as a product of the action of 1-aminocyclopropane-1-carboxylic acid synthase in the biosynthesis of ethylene.


Suppliers

H&Z Industry Co.,Ltd
HIC22208880
+
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI765930636
+
Chemlyte Solutions
CS19985994
+
Autech Industry Co.,Limited
AIC299711988
+
Indofine Chemical Co, Inc.
04-264
JieJie Group Co., Ltd.
JG24427326
+
Minakem SAS
MS12213663
Junwee Chemical Co., Ltd.
JC27758325
+
Xiamen Equation Chemical Co.,Ltd
XECC355217760
+
Daming Changda Co., Ltd.
LLB00373
+
Hangzhou Ocean Chemical Co., Ltd.
HOC366314652
+
Finetech Industry Limited
FIL277511100
+
Carbone Scientific Co., Ltd.
CS31089324
+
AK Scientific, Inc.
AS21096327
+
Xiamen Kinbester Co., Ltd.
XK28868658
+
Simagchem Corporation
SC23316993
+
Xingrui Industry Co., Limited
XIL321912876
+
Capot Chemical Co., Ltd.
11063
+
Santa Cruz Biotechnology, Inc.
202393
Dayang Chem (Hangzhou) Co.,Ltd.
DC344113764
+
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Prices & Availability




Data is processed


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Properties for 1-Aminocyclopropane-1-Carboxylic Acid

Molecular Weight:
101.1 g·mol−1
Density:
~1.4 g/cm3 (Predicted)
Melting point:
229-231 °C(lit.)
Boiling point:
~228.9° C at 760 mmHg (Predicted)
Solubility:
Soluble in DMSO, and water (40 mg/ml).
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Hazard Statements

GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
    • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:
R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
S37/39 - Wear suitable gloves and eye/face protection
Hazard Symbols:
Xi
Hazard symbol Xi
Storage temperature :
Store at 0 °C
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Alternative Distributors of [1-Aminocyclopropane-1-Carboxylic Acid]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Davos Chemical Corp. | Shanghai Chemicals & Pharmaceuticals Co., Limited | ABCR GmbH & Co. KG | Pharmasi Chemicals Co., Ltd. | TCI Europe NV | Kinfon Pharmaceutical and Chemical Service Co., Ltd. | Sanowart Group Co., Ltd. | Shanghai Boyle Chemical Co., Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd. | Ark Pharm, Inc. | Suzhou Rovathin Pharmatech Co., Ltd | Lanzhou Boc chem Co., Ltd. | Wuxi Mizat Chemical Technology Co., Ltd. | Annker Organics Co., Ltd. | Bepharm Ltd. | Shanghai Hanhong Chemical Co., Ltd. | Win-Win Chemical Co., Limited | AOKBIO Co., Ltd. | ChengDu KaiXin Technology Development Co., Ltd. | Jinan Great Chemical Co., Ltd. | Nantong Qihai Chemicals Co., Ltd. | Nanjing Dernor Pharmaceutical Technology Co., Ltd. | Shanghai HuanChuan Industry Co., Ltd | 3Way Pharm Inc. | East Chemical Industry Co., Ltd. | Kairer Chengdu Pharmaceutical Co., Ltd. | Shanghai Witofly Chemical Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | Watson International Ltd | Pangea Chemicals | BOC Sciences | Suzhou Bichal Biological Technology Co., Ltd. | Jinan Haohua Industry Co., Ltd. | Finetech Industry Limited | Suzhou Vosun Chemical Co.,Ltd. | Skyrun Industrial Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Intatrade Chemicals GmbH

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