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1-Aminocyclopropane-1-Carboxylic Acid

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Formula: C4H7NO2
CAS: 22059-21-8

Identification

Structural Formula
1-Aminocyclopropane-1-Carboxylic Acid
CAS:
22059-21-8
EINECS:
Molecular Formula:
C4H7NO2
MDL:
MFCD00009944
SMILES:
C1CC1(C(=O)O)N
Synonym:
nsc 98430 ; 1-aminocyclopropanecarbox... ; acc ; ac3c ; 1,1-accp ; h-acpc-oh ; 1-amino-1-carboxycyclopropane ; carboxycyclopropylamine ; h-(1)nhcpropn-oh ; h-acc-oh.hcl


Description

1-Aminocyclopropane-1-carboxylic Acid is a small molecule agonist at the glycine modulatory site of the NMDA receptor. Described to mimic the effects of glycine at the NMDAR, 1-Aminocyclopropane-1-carboxylic Acid competitively inhibits binding of [3H]glycine and enhances the binding of [3H]MK-801 to NMDAR-coupled cation channels similarly to glycine (though with less efficacy). 1-Aminocyclopropane-1-carboxylic Acid is shown to block convulsions and death produced by NMDA exposure, significantly reducing seizure induction and cell death of NMDA-treated hippocampal neurons. 1-Aminocyclopropane-1-carboxylic Acid is produced endogenously in the tomato and other higher plants as a product of the action of 1-aminocyclopropane-1-carboxylic acid synthase in the biosynthesis of ethylene.


Suppliers

Autech Industry Co.,Limited
AIC299711988
H&Z Industry Co.,Ltd
HIC22208880
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI765930636
Chemlyte Solutions
CS19985994
Indofine Chemical Co, Inc.
04-264
JieJie Group Co., Ltd.
JG24427326
Minakem SAS
MS12213663
Junwee Chemical Co., Ltd.
JC27758325
Xiamen Equation Chemical Co.,Ltd
XECC355217760
Daming Changda Co., Ltd.
LLB00373
Hangzhou Ocean Chemical Co., Ltd.
HOC366314652
Finetech Industry Limited
FIL277511100
Carbone Scientific Co., Ltd.
CS31089324
AK Scientific, Inc.
AS21096327
Xiamen Kinbester Co., Ltd.
XK28868658
Simagchem Corporation
SC23316993
Xingrui Industry Co., Limited
XIL321912876
Capot Chemical Co., Ltd.
11063
Santa Cruz Biotechnology, Inc.
202393
Dayang Chem (Hangzhou) Co.,Ltd.
DC344113764
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Prices & Availability




Data is processed


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Properties for 1-Aminocyclopropane-1-Carboxylic Acid

Molecular Weight:
101.1 g·mol−1
Density:
~1.4 g/cm3 (Predicted)
Melting point:
229-231 °C(lit.)
Boiling point:
~228.9° C at 760 mmHg (Predicted)
Solubility:
Soluble in DMSO, and water (40 mg/ml).
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Hazard Statements

GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
  • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:
R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
S37/39 - Wear suitable gloves and eye/face protection
Hazard Symbols:
Xi
Hazard symbol Xi
Storage temperature :
Store at 0 °C
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Alternative Distributors of [1-Aminocyclopropane-1-Carboxylic Acid]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Davos Chemical Corp. | Shanghai Chemicals & Pharmaceuticals Co., Limited | ABCR GmbH & Co. KG | Pharmasi Chemicals Co., Ltd. | TCI Europe NV | Kinfon Pharmaceutical and Chemical Service Co., Ltd. | Sanowart Group Co., Ltd. | Shanghai Boyle Chemical Co., Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd. | Ark Pharm, Inc. | Suzhou Rovathin Pharmatech Co., Ltd | Lanzhou Boc chem Co., Ltd. | Wuxi Mizat Chemical Technology Co., Ltd. | Annker Organics Co., Ltd. | Bepharm Ltd. | Shanghai Hanhong Chemical Co., Ltd. | Win-Win Chemical Co., Limited | AOKBIO Co., Ltd. | ChengDu KaiXin Technology Development Co., Ltd. | Jinan Great Chemical Co., Ltd. | Nantong Qihai Chemicals Co., Ltd. | Nanjing Dernor Pharmaceutical Technology Co., Ltd. | Shanghai HuanChuan Industry Co., Ltd | 3Way Pharm Inc. | East Chemical Industry Co., Ltd. | Kairer Chengdu Pharmaceutical Co., Ltd. | Shanghai Witofly Chemical Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | Watson International Ltd | Pangea Chemicals | BOC Sciences | Suzhou Bichal Biological Technology Co., Ltd. | Jinan Haohua Industry Co., Ltd. | Finetech Industry Limited | Suzhou Vosun Chemical Co.,Ltd. | Skyrun Industrial Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Intatrade Chemicals GmbH

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