Semi-synthetic fluorescent derivative of Actinomycin D (LS-1004); marking DNA by intercalation; used in viability/apoptosis assays; inhibitor of DNA-primed RNA polymerase and DNA polymerase. 1. Latt, S. A., Fluorescent probes of chromosome structure and replication. Can J Genet Cytol. 1977, 19 (4): 603-23. 2. Schutte, B. et al., Annexin V binding assay as a tool to measure apoptosis in differentiated neuronal cells. J. Neurosci. Methods 1998, 86, 63-69.
R26/27/28 - Very toxic by inhalation, in contact with skin and if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice S28 - After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) S36/37 - Wear suitable protective clothing and gloves S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Symbols:
T+
x
Alternative Distributors of [7-Aminoactinomycin]
Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.