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3-Amino-1,2,4-triazole

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Formula: C2H4N4
CAS: 61-82-5
search Element: triazole amino

Identification

Structural Formula
3-Amino-1,2,4-triazole
CAS:
61-82-5
EINECS:
200-521-5
Molecular Formula:
C2H4N4
MDL:
MFCD00005230
SMILES:
C1=NNC(=N1)N
Synonym:
vorox ; tr2 ; psctk ; azolan ; 3-at ; at ; ata(r) ; imd1 ; amerol ; xla


Description

3-Amino-1,2,4-triazole is a small molecule irreversible inhibitor of catalase, an enzyme responsible for converting cellular H2O2 into H2O and O2. Impeding the natural clearance of H2O2 from the cell by catalase has proven useful in studies investigating free radical-mediated damage of cardiac tissue in ischemia. 3-Amino-1,2,4-triazole also shows inhibition of imidazoleglycerol-phosphate dehydratase (HIS3) activity, which interrupts the biosynthesis of histidines. When 3-Amino-1,2,4-triazole is diazotized, the resulting 3-Diazo-1,2,4-triazole is shown to react specifically with tryptophan at acidic pH, presenting a method for determining the tryptophan content of proteins.


Suppliers

Krada CPS Industry S.L
KCIS9684840
Wuhan PharmChem Co., LTD.
WP11003300
Shandong SanYoung Industry Co., Ltd
SSI15406160
Connect Chemicals GmbH
CC9682904
Kowa American Corp.
KAC8363344
Sancai Industry Co.,Ltd.
SIC10564224
Hangzhou Lingrui Chemical Co., Ltd.
HLC15406160
scienTEST - bioKEMIX GmbH
S-B11004400
AK Scientific, Inc.
AS8362508
DSL Chemicals (Shanghai) Co., Ltd.
C001885
Xingrui Industry Co., Limited
XIL12765104
Santa Cruz Biotechnology, Inc.
202016
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CAS equal suppliers

Amitrole
Sigma-Aldrich International GmbH
SI256768
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Chemieliva Pharmaceutical Co., Ltd.
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Leap Chem Co., Ltd
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Skyrun Industrial Co., Ltd.
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Shanghai Sunwise Chemical Co., Ltd.
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Lonwin Industry Group Limited
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Autech Industry Co.,Limited
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Ascender Chemical Co.,Ltd
ACC7503000
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H&Z Industry Co.,Ltd
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Gihi Chemicals Co., Limited
GCL8103240
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OPQ Chemical Co., Ltd
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Chemlyte Solutions
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Hangzhou J&H Chemical Co., Ltd.
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Hangzhou Zhongqi Chem Co., Ltd
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Angene International Limited
AGN-PC-0ODI4W
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Hangzhou MolCore BioPharmatech Co.,Ltd.
CS22032
3-Amino-1H-1,2,4-Triazole
Biesterfeld Spezialchemie GmbH
BS22506750
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CM Fine Chemicals
CFC12755100
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Merck Schuchardt OHG
MSO15006000
3-Amino-1H-1,2,4-triazole
Key Organics Limited
PS-9367
3-Amino-1H-1,2,4-triazole, 95%
Acros Organics BVBA
AOB17106840
3-Amino-1H-1,2,4-triazole, 96%
Alfa (A Johnson Matthey Company)
A28808640

Prices & Availability




Data is processed


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Properties for 3-Amino-1,2,4-triazole

Molecular Weight:
84.08 g·mol−1
Density:
1.138
Melting point:
150-153 °C(lit.)
Boiling point:
322.2-373.2° C at 760 mmHg (Predicted)
Solubility:
Soluble in water (280 g/l) at 20° C, methanol, ethanol, chloroform, and ethyl acetate (slightly). Insoluble in ether, and acetone.
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Hazard Statements

GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
  • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization
GHS08

GHS08
Health hazard
  • Respiratory sensitization, category 1
  • Germ cell mutagenicity, categories 1A, 1B, 2
  • Carcinogenicity, categories 1A, 1B, 2
  • Reproductive toxicity, categories 1A, 1B, 2
  • Specific target organ toxicity following single exposure, categories 1, 2
  • Specific target organ toxicity following repeated exposure, categories 1, 2
  • Aspiration hazard, categories 1, 2
GHS09

GHS09
Environmental hazard
  • Acute hazards to the aquatic environment, category 1
  • Chronic hazards to the aquatic environment, categories 1, 2
  • Environmental toxicity, categories 1, 2

Safety & Transport Information

Risk Codes:
R40 - Limited evidence of a carcinogenic effect
R48/22 - Harmful: danger of serious damage to health by prolonged exposure if swallowed
R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
R61 - May cause harm to the unborn child
R63 - Possible risk of harm to the unborn child
Safety Codes:
S13 - Keep away from food, drink and animal foodstuffs
S36/37 - Wear suitable protective clothing and gloves
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S53 - Avoid exposure - obtain special instructions before use
S61 - Avoid release to the environment. Refer to special instructions/safety data sheet
Hazard Symbols:
Xn, N, T
Hazard symbol T Hazard symbol N Hazard symbol Xn
Storage temperature :
-20°C
RID/ADR certification :
UN 3077 9 / PG 3
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Alternative Distributors of [3-Amino-1,2,4-triazole]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Biosynth AG | ABCR GmbH & Co. KG | Inter-Chemical Ltd. | Junwee Chemical Co., Ltd. | Fischer Chemicals AG | Share Chemical Co., Ltd. | Gihi Chemicals Co., Limited | Lightchem Limited | Furrental Chemicals International Corp. | Rongkang Industry Co.,Ltd - (NSTU Chemicals Hanggzhou Co.,) | Santec Chemicals Corp. | TCI Europe NV | Molekula GmbH | Jin-Jiang Chemical Dyestuff Co., Ltd | Hallochem Pharma Co., Ltd. | scienTEST | Jinan Haohua Industry Co., Ltd. | Changzhou An-Yuan Imp. & Exp. Corporation | Suzhou Rovathin Pharmatech Co., Ltd | Suzhou Vosun Chemical Co.,Ltd. | Haihang Industry Co., Ltd.

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