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D(-)-2-Amino-5-phosphonovaleric acid (D-AP5)

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Formula: C5H12NO5P
CAS: 79055-68-8

Identification

Structural Formula
D(-)-2-Amino-5-phosphonovaleric acid (D-AP5)
CAS:
79055-68-8
EINECS:
Molecular Formula:
C5H12NO5P
MDL:
MFCD00078839
SMILES:
C(C[C@H](C(=O)O)N)CP(=O)(O)O
Synonym:
d-norvaline,5-phosphono- ; d-apv ; d-aminophosphonovaleric acid ; (r)-5-phosphono-2-aminovaleric acid ; death associated protein 5 ; (r)-ap-5 ; d-2-amino-5-phosphonopentanoic acid ; d-(-)-2-amino-5-phosphonopentanoicacid ; (2r)-2-amino-5-phosphonovaleric acid ; d-2-amino-5-phosphonovaleric acid ; eif4g2 ; 5-phosphono-d-norvaline ; (r)-2-amino-5-phosphonovaleric acid ; d-ap-5 ; (-)-2-amino-5-phosphonopentanoicacid ; (r)-2-amino-5-phosphonopentanoicacid ; d-ap5 ; if4g2 ; (-)-2-amino-5-phosphonovaleric acid


Description

D(-)-2-Amino-5-phosphonovaleric acid (D-AP5) is a selective antagonist of the NMDA receptor. D(-)-2-Amino-5-phosphonovaleric acid is described to antagonize amino acid-induced synaptic excitations, blocking L-aspartate and dorsal root-evoked spinal neuron excitation, without affecting cholinergic excitation induced by exogenous acetylcholine administration. Evoked electrical activity of neurons is suppressed by D(-)-2-Amino-5-phosphonovaleric acid antagonism of motoneuronal depolarizations at the NMDAR. The (+)-stereoisomer of D(-)-2-Amino-5-phosphonovaleric acid demonstrates considerably diminished NMDAR activity as compared to this (-)-isomer.


Suppliers

Santa Cruz Biotechnology, Inc.
200434
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Prices & Availability




Data is processed


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Properties for D(-)-2-Amino-5-phosphonovaleric acid (D-AP5)

Molecular Weight:
197.13 g·mol−1
Density:
1.529 g/cm3
Melting point:
245-246 °C
Boiling point:
482.1 °C at 760 mmHg
Flash point:
245.4 °C
Physical Description:
white fine crystalline powder
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Safety & Transport Information

Risk Codes:
R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
Hazard Symbols:
Xi
Hazard symbol Xi
Storage temperature :
Store at RT
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Alternative Distributors of [D(-)-2-Amino-5-phosphonovaleric acid (D-AP5)]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Jinan Haohua Industry Co., Ltd. | Salsbury Chemicals, Inc.,

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Downloads

Mol File:
-/-
MSDS:
-/-