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Amidepsine A

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Formula: C29H29 N O11
CAS: 169181-28-6
search Element: amidepsine
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Identification

Structural Formula
Amidepsine A
CAS:
169181-28-6
EINECS:
Molecular Formula:
C29H29 N O11
MDL:
SMILES:
CC1=CC(=CC(=C1C(=O)NC(C)C(=O)O)O)OC(=O)C2=C(C=C(C=C2C)OC(=O)C3=C(C=C(C=C3C)OC)OC)O
Synonym:
AmidepsineA ; FO 2942A ; Benzoic acid,2,4-dimethoxy-6-methyl-,4-[[4-[[(1-carboxyethyl)amino]carbonyl]-3-hydroxy-5-methylphenoxy]carbonyl]-3-hydroxy-5-methylphenylester (9CI)


Description

Amidepsine A is an inhibitor of DGAT (diacylglycerol acyltransferase). This shows inhibitory effect in rat liver microsomes (IC50=10.2μM) and Raji cells (IC50=15.5μM). It has excessive accumulation of triacetylglycerol produced by DGAT which may cause fatty liver, obesity, and hypertriglyceridemia, and may lead to atherosclerosis, diabetes and metabolic disorders.


Suppliers

Leap Chem Co., Ltd
LC4321296
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Santa Cruz Biotechnology, Inc.
221244
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Prices & Availability




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Properties for Amidepsine A

Molecular Weight:
567.54 g·mol−1
Density:
1.36 g/cm3 (Predicted)
Boiling point:
773.25° C at 760 mmHg (Predicted)
Solubility:
Soluble in methanol, ethyl acetate, and benzene. Insoluble in water, and hexane.
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Safety & Transport Information

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Alternative Distributors of [Amidepsine A]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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Downloads

Mol File:
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MSDS:
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