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Amastatin hydrochloride

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Formula: C21H39ClN4O8
CAS: 100938-10-1

Identification

Structural Formula
Amastatin hydrochloride
CAS:
100938-10-1
EINECS:
Molecular Formula:
C21H39ClN4O8
MDL:
MFCD00058071
SMILES:
CC(C)C[C@H]([C@@H](C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)O)O)N.Cl
Synonym:
n((2s 3r)3-amino-2-hxy-5-me.hexanoyl)-l& ; (2s,3r)-[3-amino-2-hydroxy-5-methylhexanoyl]-val-val-asp-oh hcl ; amastatin hydrochloride ; amastatin hcl ; h-(2s,3r)-ahmh-val-val-asp-oh hcl ; amastatinhydrochloridebiochemikasynthetic ; amastatin hydrate hydrochloride ; amastatin hydrochloride hydrate ; amastatin ; [(2s,3r)-3-amino-2-hydroxy-5-methylhexanoyl]-val-val-asp hydrochloride


Description

Amastatin hydrochloride is a slow, tightly binding, competitive inhibitor of human serum aminopeptidase A, human serum aminopeptidase M (CD13), pig kidney leucine aminopeptidase (LAP3), and tyrosine aminopeptidase, but not of aminopeptidase B. The compound has been used to potentiate the action of some bioactive peptides by inhibiting their degradation by aminopeptidases. Amastatin hydrochloride has been shown to slightly decrease the conversion of angiontensin II to angiotensin III, but significantly increases the potency of angiotensin III and des(Asp1)angiotensin I. In addition, the Suc-Ala-Ala-Pro-Leu-pNA amidolytic enzyme activities were completely inhibited with the addition of amastatin hydrochloride.


Suppliers

Indofine Chemical Co, Inc.
Bio-905
Santa Cruz Biotechnology, Inc.
202051
Dayang Chem (Hangzhou) Co.,Ltd.
DC14265704
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CAS equal suppliers

Amastatin.HCl
Alpha Biopharmaceuticals Co., Ltd.
AB8842652
Amastatin · HCl
Bachem AG
N-1410.0001

Prices & Availability




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Properties for Amastatin hydrochloride

Molecular Weight:
511.01 g·mol−1
Solubility:
methanol: 5 mg/mL, clear, colorless
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Safety & Transport Information

Storage temperature :
-20°C
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Alternative Distributors of [Amastatin hydrochloride]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Carl Roth GmbH + Co KG | Jinan Haohua Industry Co., Ltd.

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MSDS:
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