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α-Iodoacetamide

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Formula: C2H4INO
CAS: 144-48-9
search Element: iodoacetamide alpha

Identification

Structural Formula
α-Iodoacetamide
CAS:
144-48-9
EINECS:
205-630-1
Molecular Formula:
C2H4INO
MDL:
MFCD00008028
SMILES:
NC(=O)CI
Synonym:
usaf d-1 ; iodoacetamide ; usafd-1 ; monoiodoacetamide ; iodoethanamide ; 2-iodoacetamide ; iodacetamide ; 2-iodo-acetamid ; surauto ; iam


Description

α-Iodoacetamide is a compound used as an electrophile for covalent modification of nucleophilic residues on proteins (cysteine, methionine, histidine). When modifying the active-site residues of cysteine proteases, α-Iodoacetamide acts as an irreversible inhibitor of these enzymes.


Suppliers

Santa Cruz Biotechnology, Inc.
203320
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Prices & Availability




Data is processed


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Properties for α-Iodoacetamide

Molecular Weight:
184.96 g·mol−1
Density:
2.28 g/cm3 (Predicted)
Melting point:
92-95 °C(lit.)
Boiling point:
297.05° C at 760 mmHg (Predicted)
Solubility:
H2O: 0.5 M at 20 °C, clear, colorless
Physical Description:
yellow-brown crystals
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Hazard Statements

GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
  • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:
R25 - Toxic if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
R42/43 - May cause sensitization by inhalation and skin contact
R43 - May cause sensitisation by skin contact
R53 - May cause long-term adverse effects in the aquatic environment
Safety Codes:
S22 - Do not breathe dust
S24 - Avoid contact with skin
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37 - Wear suitable protective clothing and gloves
S37/39 - Wear suitable gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Classes:
6.1
Hazard Symbols:
T
Hazard symbol T
Storage temperature :
2-8°C
RID/ADR certification :
UN 2811 6.1 / PG 3
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Alternative Distributors of [α-Iodoacetamide]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Rongkang Industry Co.,Ltd - (NSTU Chemicals Hanggzhou Co.,) | Molekula GmbH | Chem-Impex International, Inc. | ABCR GmbH & Co. KG | Jinzhou Donghui PharmaChem Co., Ltd. | Suzhou Rovathin Pharmatech Co., Ltd | Jinan Great Chemical Co., Ltd. | East Chemical Industry Co., Ltd. | Kairer Chengdu Pharmaceutical Co., Ltd. | BOC Sciences | Jinan Haohua Industry Co., Ltd. | Pfaltz & Bauer, Inc. | Gihi Chemicals Co., Limited

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