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N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-epsilon-trifluoracetyl-L-lysine

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Formula: C23H23F3N2O5
CAS: 76265-69-5
search Element: fluorenylmethyloxycarbonyl trifluoracetyl epsilon lysine alpha
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Identification

Structural Formula
N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-epsilon-trifluoracetyl-L-lysine
CAS:
76265-69-5
EINECS:
Molecular Formula:
C23H23F3N2O5
MDL:
MFCD00153360
Synonym:
n-α-fmoc-n-ε-tritfluoroacetyl-l-lysine ; fmoc-n-epsilon-trifluoroacetyl-l-lysine ; n(alpha)-fmoc-n(epsilon)-trifluoro- ; n-alpha-fmoc-n-epsilon-trifluoroacetyl-l-lysine ; fmoc-n-e-tfa-l-lysine ; fmoc-l-lys(tfa)-oh ; fmoc-lys(tfa)-oh ; fmoc-n-epsilon-tfa-l-lysine ; na-fmoc-ne-trifluoroacetyl-l-lysine ; n^a-fmoc-n^e-trifluoracetyl-l-lysine, 95%


Description

Building block with side protection orthogonal to Fmoc/tBu strategy. Can be used for side specific derivatization, for example for TFA mediated in situ cyclization, which is taking advantage of intermediate aspartamide formation. Reference: A Tandem In Situ Peptide Cyclization through Trifluoroacetic Acid Cleavage; Koushik Chandra, Tapta Kanchan Roy, Deborah E. Shalev, Abraham Loyter, Chaim Gilon, R. Benny Gerber, and Assaf Friedler; Angew. Chem. Int. Ed. 2014; 53: 9450-9455. DOI: 10.1002/anie.201402789.


Suppliers

Iris Biotech GmbH
FAA1588
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Prices & Availability




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Properties for N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-epsilon-trifluoracetyl-L-lysine

Molecular Weight:
464.43 g·mol−1
Melting point:
170-175°C
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Safety & Transport Information

Storage temperature :
2-8°C
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Alternative Distributors of [N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-epsilon-trifluoracetyl-L-lysine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

ABCR GmbH & Co. KG

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