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N-alpha-(9-Fluorenylmethyloxycarbonyl)-O-(t-butyl-dimethyl-silyl)-L-serine

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Formula: C24H31 N O5 Si
CAS: 146346-81-8

Identification

Structural Formula
N-alpha-(9-Fluorenylmethyloxycarbonyl)-O-(t-butyl-dimethyl-silyl)-L-serine
CAS:
146346-81-8
EINECS:
Molecular Formula:
C24H31 N O5 Si
MDL:
MFCD02092931
Synonym:
fmoc-o-t-butyldimethylsilyl-l-serine ; fmoc-serine(bsi)-oh ; fmoc-ser(tbume 2si)-oh ; l-serine,o-[(1,1-dimethylethyl)dimethylsilyl]-n-[(9h-fluoren-9-ylmethoxy)carbonyl]- ; fmoc-o-tert-butyldimethylsilyl-l-serine ; fmoc-ser(bsi)-oh ; n-alpha-(9-fluorenylmethoxycarbonyl)-o-t-butyldimethylsilyl-l-serine ; o-[(1,1-dimethylethyl)dimethylsilyl]-n-[(9h-fluoren-9-ylmethoxy)carbonyl]-l-serine ; fmoc-ser(tbdms)-oh


Description

The TBDMS protecting group of the serine hydroxy function is more labile towards TFA than tBu and can selectively be cleaved in the presence of Boc/tBu with tetrabutylammonium fluoride in DMF. However, Fmoc is also being removed under these conditions! Reference: Fischer P.M.; Tetrahedron Lett. 1992; 33: 7605.


Suppliers

Iris Biotech GmbH
FAA6510
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Prices & Availability




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Properties for N-alpha-(9-Fluorenylmethyloxycarbonyl)-O-(t-butyl-dimethyl-silyl)-L-serine

Molecular Weight:
441.59 g·mol−1
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Safety & Transport Information

Storage temperature :
-15°C
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Alternative Distributors of [N-alpha-(9-Fluorenylmethyloxycarbonyl)-O-(t-butyl-dimethyl-silyl)-L-serine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Rif Life Science Co., Limited

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