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N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-aspartic acid beta-cyclohexyl ester

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Formula: C25H27NO6
CAS: 130304-80-2
search Element: fluorenylmethyloxycarbonyl cyclohexyl aspartic alpha ester acid beta
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Identification

Structural Formula
N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-aspartic acid beta-cyclohexyl ester
CAS:
130304-80-2
EINECS:
Molecular Formula:
C25H27NO6
MDL:
MFCD00135420
Synonym:
fmoc-asp(ochx)-oh ; fmoc-l-asparatic acid-b-cyclohexylester ; fmoc-asp(ochex)-oh ; fmoc-l-asp(ochx)-oh ; fmoc-aap(ochex)-oh ; fmoc-asp-(ochx)-ph ; fmoc-l-asp(chx)-oh ; fmoc-l-aspartic acid β-cyclohexyl ester ; fmoc-aspartic acid(ochex) ; fmoc-asn(ochex)-oh


Description

Building block with side protection orthogonal to Fmoc/tBu strategy. Can be used for side specific derivatization, for example for TFA mediated in situ cyclization, which is taking advantage of intermediate aspartamide formation. Reference: A Tandem In Situ Peptide Cyclization through Trifluoroacetic Acid Cleavage; Koushik Chandra, Tapta Kanchan Roy, Deborah E. Shalev, Abraham Loyter, Chaim Gilon, R. Benny Gerber, and Assaf Friedler; Angew. Chem. Int. Ed. 2014; 53: 9450-9455. DOI: 10.1002/anie.201402789.


Suppliers

Iris Biotech GmbH
FAA1705
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Prices & Availability




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Properties for N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-aspartic acid beta-cyclohexyl ester

Molecular Weight:
437.48 g·mol−1
Melting point:
118-132°C
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Safety & Transport Information

Storage temperature :
-15°C
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Alternative Distributors of [N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-aspartic acid beta-cyclohexyl ester]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

ABCR GmbH & Co. KG

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MSDS:
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