Identification
N-alpha-t-Butyloxycarbonyl-beta,beta-dimethyl-proline (rac.)
Molecular Formula:
C1 2 H2 1 N O4
Synonym:
1-[(tert-butyl)oxycarbonyl]-3,3-dimethylpyrrolidine-2-carboxylic acid ; rac n-boc-3,3-dimethyl-2-pyrrolidenecarboxylic acid ; 1,2-pyrrolidinedicarboxylic acid, 3,3-dimethyl-, 1-(1,1-dimethylethyl) ester ; (r,s)-boc-3,3-dimethyl-proline ; 3,3-dimethyl-1,2-pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) ester ; 1-(tert-butoxycarbonyl)-3,3-dimethylpyrrolidine-2-carboxylic acid ; boc-3,3-dimethyl-proline ; 1,2-pyrrolidinedicarboxylicacid, 3,3-dimethyl-, 1-(1,1-dimethylethyl) ester ; (r,s)-boc-3,3-dimethyl-pyrrolidine-2-carboxylic acid
Description
beta,beta-Dimethylation of amino acids stabilizes appropriate peptides towards digestion by proteases. Reference: Benzyl 2-Cyano-3,3-Dimethyl-1-pyrrolidinecarboxylate, a Versatile Intermediate for the Synthesis of 3,3-Dimethylproline Derivatives; Jesus R. Medina, Charles W. Blackledge, Karl F. Erhard, Jeffrey M. Axten, and William H. Miller; J. Org. Chem. 2008; 73: 3946-3949. DOI: 10.1021/jo7027163.
Suppliers
Iris Biotech GmbH
BAA2860
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N-alpha-tert-Butyloxycarbonyl-beta,beta-dimethyl-proline (rac.)
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Properties
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Properties for N-alpha-t-Butyloxycarbonyl-beta,beta-dimethyl-proline (rac.)
Molecular Weight:
243.30 g·mol−1
Physical Description:
white solid
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