Acyclovir | CAS 59277-89-3 | Chemical-Suppliers

Element: acyclovir

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C-S » Chemicals » acyclovir-PX69774

Identification

Acyclovir

CAS:

59277-89-3

EINECS:

261-685-1

Molecular Formula:

C₈H₁₁N₅O₃

MDL:

MFCD00057880

SMILES:

NC1=NC(=O)C2=C(N1)N(COCCO)C=N2

Synonym:

zoviax ; zyclir ; vimrax ; vipral ; w-248-u ; aclovir ; bw248u ; virorax ; poviral ; acv

Description

Acyclovir is an antiviral compound that can be used to induce apoptosis in cells transfected with herpes simplex virus thymidine kinase (HSV-TK). The compound may exert inhibitory effects through the alterations of the cell cycle in leukemia cells lines, such as p185BCR-ABL expressing OM9:22 cells, by synchronizing the G₀/G₁ phase. Formation of acycloguanosine triphosphate occurs through the phosphorylation of HSV-TK and can inhibit the viral DNA polymerase. Acyclovir also has the ability to inhibit the proliferation of the fibroblast cells, NIH 3T3, transformed with v-abl or bcr-abl.

Suppliers

Chemlyte Solutions

CS162486

Ambeed, Inc.

A118981

Aozeal Certified Standards (AOCS), Inc.

A0003.00

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI6212484

H&Z Industry Co.,Ltd

HIC180720

Wuhan PharmChem Co., LTD.

WP225675

Recordati S.P.A.

RS144432

IPOCHEM Sp. z o.o.

ISZO162810

Indofine Chemical Co, Inc.

Bio-478

EXCELLA GmbH

E108216

Biddle Sawyer Corp.

BSC171684

B.M.P. Bulk Medicines & Pharmaceuticals GmbH

BBMP3961980

Arcadia Biotechnology

AB189567

AXO Industry SA

AIS135540

BoomKing Industrial Co.,Limited

BIC2791116

Xiamen Equation Chemical Co.,Ltd

XECC2881440

Hainan Zhongxin Chemical Co., Ltd.

HZC3061224

Aecochem Corp.

AC126378

CSNpharm, Inc.

CSN10120

Wanko Chemical Co., Ltd.

WC216648

Sigma-Aldrich International GmbH

SI288864

scienTEST - bioKEMIX GmbH

S-B225900

Pharmacore Co., Limited

PL207621

Acinopeptide Co., Ltd.

A198396

CM Fine Chemicals

CFC153612

Simagchem Corporation

SC189567

Xingrui Industry Co., Limited

XIL2611044

Capot Chemical Co., Ltd.

9572

Amadis Chemical Company Limited

ACCL2791395

Leap Chem Co., Ltd

LC162486

Santa Cruz Biotechnology, Inc.

202906

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Angene International Limited

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Acyclovir Pharmaceutical Secondary Standard; Certified Reference Material

Ascender Chemical Co.,Ltd

ACC1277551100

Prices & Availability

Data is processed

Properties for Acyclovir

Molecular Weight:

225.2 g·mol−1

Density:

~1.8 g/cm³ (Predicted)

Melting point:

256-257 °C

Solubility:

H₂O: 0.7 mg/mL

Hazard Statements

GHS03
Harmful

Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, categories 2, 3
Eye irritation, category 2A
Skin sensitization, category 1
Specific target organ toxicity following single exposure, category 3
- Respiratory tract irritation
- Narcotic effects

Not used

with the "skull and crossbones" pictogram
for skin or eye irritation if:
the "corrosion" pictogram also appears
the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:

R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
R40 - Limited evidence of a carcinogenic effect

Safety Codes:

S22 - Do not breathe dust
S23 - Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer)
S24/25 - Avoid contact with skin and eyes
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing

Hazard Classes:

irritant

Hazard Symbols:

Xi, Xn

Storage temperature :

-20°C

Alternative Distributors of [Acyclovir]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified