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Aconitine

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Formula: C34H47NO11
CAS: 302-27-2
search Element: aconitine

Identification

Structural Formula
Aconitine
CAS:
302-27-2
EINECS:
206-121-7
Molecular Formula:
C34H47NO11
MDL:
MFCD00082375
SMILES:
CCN1C[C@@]2(COC)C3[C@@H](OC)C4[C@@H]1C3([C@@H]1C[C@@]3(O)[C@H](OC(=O)C5=CC=CC=C5)[C@@H]1[C@]4(OC(C)=O)[C@@H](O)[C@@H]3OC)[C@@H](C[C@H]2O)OC
Synonym:
aconitie ; aconitane ; aconitin ; aconitine(sh) ; adynerin(p) ; aconitine(p) ; aconitine ; aconitinestandard ; acotinine ; aconitine std.


Description

Aconitine is a lipid-soluble and potent neurotoxin that activates voltage gated sodium channels. It can inhibit non-quantal acetylcholine release and can induce neuromuscular blockage, specifically blocking the nerve compound action potential. Studies show that aconitine is toxic to neuron cells at a concentration of 2% and that it can block tetrodotoxin-sensitive Na+channels.


Suppliers

Chengdu Pufeide Biotech. Co., Ltd
CPB2971188
Indofine Chemical Co, Inc.
06-193
X´ian Taicheng Chem Co., Ltd
XTC2611044
Sigma-Aldrich International GmbH
SI288864
Pharmacore Co., Limited
PL207621
Acinopeptide Co., Ltd.
A198396
Leap Chem Co., Ltd
LC162486
Santa Cruz Biotechnology, Inc.
202441
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Properties for Aconitine

Molecular Weight:
645.74 g·mol−1
Density:
1.38 g/cm3
Melting point:
200-205 °C (dec.)
Boiling point:
717.21° C
Solubility:
Soluble in 100% ethanol (35mg/ml); almost insoluble in water (0.3mg/ml)
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Safety & Transport Information

Risk Codes:
R26/28 - Very toxic by inhalation and if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S24 - Avoid contact with skin
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Classes:
6.1(a)
Hazard Symbols:
T+, Xi
Hazard symbol Xi Hazard symbol T+
Storage temperature :
Refrigerator
RID/ADR certification :
UN 1544 6.1 / PG 1
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Alternative Distributors of [Aconitine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Santec Chemicals Corp. | Molekula GmbH | CCS. CHEM. Co., Ltd. | 3B Scientific Corporation | Northchem (Tianjin) International Trading Co., Ltd. | Chengdu Biopurify Phytochemicals Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd. | Jinan Great Chemical Co., Ltd. | Cfm Oskar Tropitzsch GmbH | BOC Sciences | Hangzhou JingHang Biotechnology Co., Ltd. | Jinan Haohua Industry Co., Ltd. | Pfaltz & Bauer, Inc. | Haihang Industry Co., Ltd.

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