N-Acetyl-L-cysteine | CAS 616-91-1

Element: cysteine acetyl

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C-S » Chemicals » acetyl-cysteine-PX81128

Identification

N-Acetyl-L-cysteine

CAS:

616-91-1

EINECS:

210-498-3

Molecular Formula:

C₅H₉NO₃S

MDL:

MFCD00004880

SMILES:

CC(=O)N[C@@H](CS)C(=O)O

Synonym:

acc ; lnac ; mucret ; acc1 ; acaca ; nac-tb ; lnal ; inspir ; brunac ; fabrol

Description

N-Acetyl-L-cysteine is an acetylated amino acid with antioxidant and mucolytic properties. These two activities have made N-Acetyl-L-cysteine particularly relevant in cystic fibrosis studies, where the antioxidant/reducing character of the compound is described to ameliorate the characteristic systemic redox imbalance state of cystic fibrosis and the mucolytic properties of the compound are shown to impede upon the congestion and inflammation correlated to this redox state. As a mucolytic, N-Acetyl-L-cysteine serves to dissipate disulfide bonds across mucoproteins, loosening and clearing the viscosity of sputum. N-Acetyl-L-cysteine shows complimentary action to glutathione, both demonstrating antioxidant activity through their thiol functionality, and both are shown to protect against peroxidative stress related to septic shock. N-Acetyl-L-cysteine has also been shown to induce apoptosis in vascular smooth muscle cells, indicating that these cells respond differently to changes in reduction-oxidation state than other tissues that are normally protected by the presence of antioxidants. This observation in vascular smooth muscle cells indicates N-Acetyl-L-cysteine as an interventional tool upon arteriosclerotic proliferation of these cells.

Suppliers

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI13115244

Lori Industry Co., Ltd

LI4181254

Shandong Lanhai Industry Co.,Ltd.

SLIC6273135

XD BIOCHEMS Ltd

XB285855

H&Z Industry Co.,Ltd

HIC3801520

Krada CPS Industry S.L

KCIS4182090

OPQ Chemical Co., Ltd

OC3991197

Nantong Xindao Biotech Ltd

NXB4941976

Create Chemical Co., Ltd.

CC4751425

Chemlyte Solutions

CS3421026

Kyowa Hakko USA, Inc.

KHU3991596

Marcor Development Corporation

MDC5702280

WG Critical Care, LLC

WCCL3991995

Indofine Chemical Co, Inc.

Bio-458

AIDP, Inc.

A190380

Ningbo Pangs Chem Co., Ltd.

NPC5132052

Fabrichem, Inc.

F285570

X´ian Taicheng Chem Co., Ltd

XTC5512204

Hangzhou Verychem Science & Technology Co., Ltd.

HVST9124560

Shanghai UCHEM Inc.

UCHEM-6051

Hangzhou Keying Chem Co., Ltd.

HKC5702280

Wanko Chemical Co., Ltd.

WC4561368

scienTEST - bioKEMIX GmbH

S-B4751900

Hangzhou Ocean Chemical Co., Ltd.

HOC6272508

Carbone Scientific Co., Ltd.

CS5321596

CM Fine Chemicals

CFC3231292

AK Scientific, Inc.

AS3611083

Xiamen Kinbester Co., Ltd.

XK4941482

Xingrui Industry Co., Limited

XIL5512204

Capot Chemical Co., Ltd.

12963

Zehao Industry Co., Ltd.

ZI4561368

BOC Sciences

BS228684

Santa Cruz Biotechnology, Inc.

202232

Dayang Chem (Hangzhou) Co.,Ltd.

DC5892356

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Manchester Organics Limited

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BLD Pharmatech Ltd

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Prices & Availability

Data is processed

Properties for N-Acetyl-L-cysteine

Molecular Weight:

163.19 g·mol−1

Density:

1.30 g/cm³ (Predicted)

Melting point:

106-108 °C(lit.)

Boiling point:

407.68° C at 760 mmHg (Predicted)

Solubility:

H₂O: 100 mg/mL with heating

Safety & Transport Information

Risk Codes:

R36/37/38 - Irritating to eyes, respiratory system and skin

Safety Codes:

S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes

Storage temperature :

2-8°C

Alternative Distributors of [N-Acetyl-L-cysteine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified