ABT 724 trihydrochloride | CAS 70006-24-5

Element: trihydrochloride

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Identification

ABT 724 trihydrochloride

CAS:

70006-24-5

EINECS:

Molecular Formula:

C₁₇H₂₂Cl₃N₅

MDL:

MFCD08703101

SMILES:

C1CN(CCN1CC2=NC3=CC=CC=C3N2)C4=CC=CC=N4.Cl.Cl.Cl

Synonym:

abt 724 ; abt 724 trihydrochloride ; 2-[[4-(2-pyridinyl)-1-piperazinyl]methyl]-1h-benzimidazole trihydrochloride ; 2-[[4-(2-pyridinyl)-1-piperazinyl]methyl]-1h-benzimidazole

Description

ABT 724 trihydrochloride is a selective D4DR (dopamine D₄ receptor) partial agonist with an EC₅₀=12.4nM. It is known that ABT 724 trihydrochloride aids sildenafil's ability to inhibit cGMP-specific phosphodiesterase type 5. cGMP-specific phosphodiesterase type 5 catalyzes the hydrolysis of 3',5'-cyclic guanosine monophosphate (cGMP). As a result ABT 724 trihydrochloride increases intracavernosal pressure. Studies suggest that sildenafil can enhance neuro-, synapto- and angiogenesis in rat models of stroke, via its ability to increase vasodilation.

Suppliers

Santa Cruz Biotechnology, Inc.

203489

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CAS equal suppliers

ABT 724

Hangzhou J&H Chemical Co., Ltd.

HJC217868

2-((4-(Pyridin-2-yl)piperazin-1-yl)methyl)-1H-benzo[d]imidazole

BLD Pharmatech Ltd

BP1247437422

Prices & Availability

Data is processed

Properties for ABT 724 trihydrochloride

Molecular Weight:

402.74908 g·mol−1

Boiling point:

605.4° C at 760 mmHg (Predicted)

Solubility:

Soluble in water (100 mM).

Safety & Transport Information

Storage temperature :

Desiccate at +4 °C

Alternative Distributors of [ABT 724 trihydrochloride]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Shanghai Elittes Organics Co., Ltd. | Medilink Pharmachem