ABT-491 hydrochloride | CAS 189689-94-9

Element: hydrochloride

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C-S » Chemicals » abt-hydrochloride-PX78065

Identification

ABT-491 hydrochloride

CAS:

189689-94-9

EINECS:

Molecular Formula:

C₂₈H₂₂ F N₅ O₂ . Cl H

MDL:

SMILES:

Cl.CN(C)C(=O)N1C=C(C(=O)C2=CC=C(CN3C(C)=NC4=C3C=CN=C4)C(F)=C2)C2=C1C=CC=C2C#C

Synonym:

a 137491 ; 1h-indole-1-carboxamide,4-ethynyl-3-[3-fluoro-4-[(2-methyl-1h-imidazo[4,5-c]pyridin-1-yl)methyl]benzoyl]-n,n-dimethyl-,hydrochloride (1:1) ; 1h-indole-1-carboxamide,4-ethynyl-3-[3-fluoro-4-[(2-methyl-1h-imidazo[4,5-c]pyridin-1-yl)methyl]benzoyl]-n,n-dimethyl-,monohydrochloride (9ci) ; abt 491 ; a-137491, 4-ethynyl-n,n-dimethyl-3-[3-fluoro-4-[(2-methyl-1h-imidazo-[4,5-c]pyridin-1-yl)methyl]benzoyl]-1h-indole-1-carboxamide hydrochloride

Description

ABT-491 hydrochloride is a highly potent, selective and orally active platelet-activating factor receptor (PAF-R) antagonist. (K_i = 0.6 nM in human platelets.)