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Abiraterone acetate

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Formula: C26H33NO2
CAS: 154229-18-2
search Element: abiraterone acetate
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Identification

Structural Formula
Abiraterone acetate
CAS:
154229-18-2
EINECS:
Molecular Formula:
C26H33NO2
MDL:
MFCD00934213
SMILES:
CC(=O)O[C@H]1CC[C@]2(C)[C@H]3CC[C@@]4(C)[C@@H](CC=C4C4=CC=CN=C4)[C@@H]3CC=C2C1
Synonym:
3β-acetoxy-17-(3-pyridyl)androsta-5,16-diene ; abiraterone acetate(cb7630) ; abiraterone acetate ester ; cb 7630 ; abiraterone acetate, >=99% ; abirteroneacetate ; 17-(3-pyridyl)-5,16-androstadien-3beta-acetate ; abiraterone acetate impurity ; abiraterone acotate ; abiraterone acetate


Description

Abiraterone acetate has been seen to be a novel steroidal inhibitor of CYP17A1(C17,20 lyase), a cytoochrome P450 complex, a rate-limiting enzyme in androgen biosynthesis resulting in inhibtion of testosterone production in both the adrenals and the testes. It has been observed to decrease the DHEA, androstenedione and testosterone. The compound has been shown to be approximately 21-24 times more potent than ketoconazole and liarozole in CYP17A1 lyase inhibition. In medicine, Abiraterone is used for treating prostate cancer.


Suppliers

Shandong SanYoung Industry Co., Ltd
SSI13305320
+
Chemlyte Solutions
CS6842052
+
Autech Industry Co.,Limited
AIC10264104
+
FUDI Chemical Co. Ltd.
FCC8363344
+
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI262210488
+
Guangzhou Topwork Chemical Co., Ltd.
GTC13685472
+
Hangzhou Cherry Pharmaceutical Technology Co., Ltd.
HCPT19389690
+
Chemvon Biotechnology Co. Ltd.
CBC11404560
+
BoomKing Industrial Co.,Limited
BIC11784712
+
Xiamen Equation Chemical Co.,Ltd
XECC12166080
+
Daming Changda Co., Ltd.
DC9122736
+
Aecochem Corp.
AC5321596
+
Hangzhou Lingrui Chemical Co., Ltd.
HLC13305320
+
scienTEST - bioKEMIX GmbH
S-B9503800
+
Hefei Hirisun Pharmatech Co., Ltd
HR130670
+
AK Scientific, Inc.
AS7222166
+
Simagchem Corporation
SC7982394
+
BOC Sciences
BS4561368
+
Leap Chem Co., Ltd
LC6842052
+
Santa Cruz Biotechnology, Inc.
207240
Dayang Chem (Hangzhou) Co.,Ltd.
DC11784712
+
Get Quick Quote

CAS equal suppliers

CB7630
Excenen Pharmatech Co., Ltd.
EX-A107
Abiraterone Acetate D4
Santa Cruz Biotechnology, Inc.
sc-217550
Abiraterone Acetate - Labeled d4
Santa Cruz Biotechnology, Inc.
sc-352989
17-(3-pyridyl)-5,16-androstadien-3beta-acetate
Chemieliva Pharmaceutical Co., Ltd.
CP805024150
17-(3-Pyridyl)-5,16-androstadien-3beta-acetate
Capot Chemical Co., Ltd.
28185
17-(3-pyridyl)-5,16-androstadien-3beta-acetate
Medibro Corporation Limited
MCL621024840
17-(3-pyridyl)-5,16-androstadien-3beta-acetate
Pharmacore Co., Limited
PL529015870
17-(3-Pyridyl)-5,16-androstadien-3beta-acetate
Xingrui Industry Co., Limited
XIL667026680
17-(3-Pyridyl)-5,16-androstadien-3beta-acetate
H&Z Industry Co.,Ltd
HIC460018400
(3beta)-17-(3-Pyridinyl)-androsta-5,16-dien-3-ol acetate (ester)
Jinan Honestpharm Co., Ltd
JH1497644928

Prices & Availability




Data is processed


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Properties for Abiraterone acetate

Molecular Weight:
391.55 g·mol−1
Density:
~1.1 g/cm3 (Predicted)
Melting point:
127-130 °C
Boiling point:
~506.7° C at 760 mmHg (Predicted)
Solubility:
Soluble in methanol (sparingly), water (<1 mg/ml at 25° C), DMF (~16 mg/ml), ethanol (28 mg/ml at 25° C), and DMSO (~2 mg/ml).
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Hazard Statements

GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
    • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Storage temperature :
-20 °C Freezer
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Alternative Distributors of [Abiraterone acetate]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

BOC Sciences | Jinan Great Chemical Co., Ltd. | Gihi Chemicals Co., Limited | Apichem Chemical Technology Co., Ltd. | Watson International Ltd | scienTEST | Chongqing Pharmaceutical Research Institute Co., Ltd. | Clearsynth Canada INC. | Suzhou Rovathin Pharmatech Co., Ltd | Suzhou Vosun Chemical Co.,Ltd. | Wuhan Sunrise Technology Development Company Ltd. | ShangHai Biochempartner Co., Ltd. | Taizhou Bolon Pharmachem Co.,Ltd.. / Bolon Pharm & Chem Co., Ltd. | Suzhou Sibian Chemical Technology Co., Ltd. | 3Way Pharm Inc. | Suzhou Bichal Biological Technology Co., Ltd. | Sino Rarechem Labs Co. Ltd. | Beijing Yangguang Furuide Chemical Co., Ltd. | Wanko Chemical Co., Ltd. | Jinan Aery Pharmaceutical Co,.Ltd. | All Right Chemical Co., Ltd.

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