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1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine

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Formula: C41H78NO8P
CAS: 4004-05-1

Identification

Structural Formula
1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
CAS:
4004-05-1
EINECS:
Molecular Formula:
C41H78NO8P
MDL:
MFCD00057986
SMILES:
CCCCCCCCC=C/CCCCCCCC(=O)OC[C@H](COP(O)(=O)OCCN)OC(=O)CCCCCCCC=C/CCCCCCCC
Synonym:
18:1 pe ; l-a-phosphatidylethanolamine dioleoyl ; dioleoylphosphatidylethanolamine ; 1,2-dioleoyl-sn-glycero-3-phosphorylethanolamine ; dioleoyl phosphoethanolamine ; ethanol, 2-amino-,dihydrogen phosphate (ester), monoester with 1,2-diolein, l- (8ci) ; 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine ; 9-octadecenoic acid(9z)-,1,1'-[(1r)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl]ester ; pe(18:1(9z)/18:1(9z)) ; l-beta,gamma-dioleoyl-alpha-cephalin ; 9-octadecenoicacid (9z)-, (1r)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediylester (9ci) ; 1,2-dioleoyl-sn-glycero-3-phosphatidylethanolamine ; l-?,?-dioleoyl-?-cephalin ; 9-octadecenoic acid (z)-,1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester, (r)- ; dioleoyl phosphatidyl ethanolamine ; dioleoyl-l-a-phosphatidylethanolamine ; olein, 1,2-di-, 2-aminoethyl hydrogen phosphate, l- (8ci) ; coatsome me-8181 (dope) ; coatsome mc 8181 ; 1,2-dioleoyl-sn-glycero-3-pe ; dope ; coatsome me8181


Description

1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) is a phospholipid emulsifier that has been used for improved DNA-liposome complex transport across membranes. Commonly used with the cationic emulsifier DOTAP ( 3-trimethylammonium-propane)(sc-202589), DOPE reduces the toxic effects of DOTAP alone and has been shown to have a high DNA trapping efficiency of 89% at a DOTAP:DOPE ratio of 2:1 in emulsions. The compound is ideal for use in gene transfer studies for both conditions with serum, in vivo, and without.


Suppliers

Autech Industry Co.,Limited
AIC24309720
Lori Industry Co., Ltd
LI19805940
Create Chemical Co., Ltd.
CC22506750
Santa Cruz Biotechnology, Inc.
202002
Dayang Chem (Hangzhou) Co.,Ltd.
DC279011160
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CAS equal suppliers

DOPE
BOC Sciences
BS48144
Dioleoyl phosphoethanolamine
Chemieliva Pharmaceutical Co., Ltd.
CP19605880
Dioleoyl phosphoethanolamine
Leap Chem Co., Ltd
LC10083024
Dioleoyl phosphoethanolamine
Finipharma Ltd
F7841568
1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, fluorescein-labeled
Santa Cruz Biotechnology, Inc.
sc-297912
(Z)-(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dioleate
BLD Pharmatech Ltd
BP1663249896

Prices & Availability




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Properties for 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine

Molecular Weight:
744.03 g·mol−1
Density:
1.008 g/cm3
Boiling point:
759.2 °C at 760 mmHg
Flash point:
413 °C
Solubility:
Soluble in water (partly), chloroform, methanol, 100% ethanol, 2-propanol, tetrahydrofurane, methylene chloride, and CHCl3:MeOH (9:1) (25 mg/ml).
Physical Description:
lyophilized powder
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Safety & Transport Information

Risk Codes:
R20 - Harmful by inhalation
R22 - Harmful if swallowed
R36/38 - Irritating to eyes and skin
R38 - Irritating to skin
R40 - Limited evidence of a carcinogenic effect
R48/20/22 - Harmful: danger of serious damage to health by prolonged exposure through inhalation and if swallowed
R63 - Possible risk of harm to the unborn child
R67 - Vapours may cause drowsiness and dizziness
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37 - Wear suitable protective clothing and gloves
Hazard Symbols:
Xi
Hazard symbol Xi
Storage temperature :
-20°C
RID/ADR certification :
UN 1888 6.1 / PG 3
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Alternative Distributors of [1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Jinan Great Chemical Co., Ltd.

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