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N-Desmethyl Sildenafil

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Identification

Structural Formula
N-Desmethyl Sildenafil
CAS:
EINECS:
Molecular Formula:
MDL:
SMILES:
CCCC1=NN(C)C2=C1N=C(NC2=O)C1=CC(=CC=C1OCC)S(=O)(=O)N1CCNCC1
Synonym:


Description

N-Desmethyl Sildenafil is a metabolite of Sildenafil. Sildenafil is a selective inhibitor of the type 5 cGMP phosphodiesterase (PDE5 inhibitor) which catalyzes the hydrolysis of 3',5'-cyclic guanosine monophosphate (cGMP). As a PDE5 inhibitor, Sildenafil has been reported to enhance neuro-, synapto- and angiogenesis in rat models of stroke and also is reported to be a mild vasodilator. Sildenafil has also been shown to prevent indomethacin-induced small intestinal ulceration formation through an NO/cGMP- dependent mechanism.


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Properties for N-Desmethyl Sildenafil

Solubility:
Soluble in methanol, chloroform, and dichloromethane.
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Safety & Transport Information

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Alternative Distributors of [N-Desmethyl Sildenafil]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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MSDS:
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