Cytochalasin E, Aspergillus clavatus | CAS 36011-19-5

Element: cytochalasin aspergillus clavatus

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Identification

Cytochalasin E, Aspergillus clavatus

CAS:

36011-19-5

EINECS:

252-835-7

Molecular Formula:

C₂₈H₃₃NO₇

MDL:

MFCD00005178

SMILES:

C[C@H]1C/C=C/[C@H]2[C@H]3[C@](O3)([C@H]([C@@H]4[C@]2(C(=O)N[C@H]4CC5=CC=CC=C5)OC(=O)O/C=C/[C@@](C1=O)(C)O)C)C

Synonym:

cytochalasin e, aspergillus clavatus ; (7s,13e,16s,18r,19e)-18-dimethyl-10-phenyl ; cytochalasin e ; cytochalacine ; cytochalicine ; cytochalasin 3 ; cytochalasin e(rg) ; cytochalasin e from aspergillus & ; cytochalasin e(rg) please call ; cytochalasin e from aspergillusclavatus

Description

Cytochalasin E, Aspergillus clavatus is used in actin polymerization studies. Cytochalasin E is a metabolite of the fungus Aspergillus clavatus which binds to the barbed end of actin filaments resulting in inhibition of both the association and dissociation of subunits. Used as a tool for cytological research. The class of Cytochalasin fungal toxins are related by their chemical structure characterized by a highly substituted hydrogenated isoindole ring to which is fused a macrocyclic ring. As opposed to Cytochalasins A and B, Cytochalasin E does not inhibit monosaccharide transport across the plasma membrane.
Other Cytochalasins available: Cytochalasin C; Cytochalasin D (sc-201442); Cytochalasin H (sc-202119); Cytochalasin J (sc-202120)

Suppliers

Santa Cruz Biotechnology, Inc.

202561

Dayang Chem (Hangzhou) Co.,Ltd.

DC446417856

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Prices & Availability

Data is processed

Properties for Cytochalasin E, Aspergillus clavatus

Molecular Weight:

495.56 g·mol−1

Density:

1.31 g/cm³ (Predicted)

Melting point:

206 °C

Boiling point:

705.06° C at 760 mmHg (Predicted)

Solubility:

Soluble in DMSO (50 mg/ml), EtOAc, ethyl acetatea (5 mg/ml), ethanol, methanol, DMF, chloroform, acetone, dichloromethane, and water (sparingly).

Hazard Statements

GHS06
Toxic

Acute toxicity (oral, dermal, inhalation), categories 1, 2, 3

Safety & Transport Information

Risk Codes:

R26/27/28 - Very toxic by inhalation, in contact with skin and if swallowed
R63 - Possible risk of harm to the unborn child

Safety Codes:

S28 - After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer)
S36/37 - Wear suitable protective clothing and gloves
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)

Hazard Classes:

6.1(a)

Hazard Symbols:

T+, T

Storage temperature :

-20°C

RID/ADR certification :

UN 1544 6.1 / PG 2

Alternative Distributors of [Cytochalasin E, Aspergillus clavatus]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.

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