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Carvedilol

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Formula: C24H26N2O4
CAS: 72956-09-3
search Element: carvedilol

Identification

Structural Formula
Carvedilol
CAS:
72956-09-3
EINECS:
Molecular Formula:
C24H26N2O4
MDL:
MFCD00864692
SMILES:
COC1=CC=CC=C1OCCNCC(COC2=CC=CC3=C2C4=CC=CC=C4N3)O
Synonym:
carca ; artist ; cadilan ; kredex ; coreg ; dq-2466 ; artione ; carloc ; querto ; carvas


Description

Carvedilol is a AR (α1 and β-adrenergic receptor) antagonist with antioxidant properties. Studies show that the receptors α1D-AR and α1B-AR have a greater affinity for Carvedilol in comparison to the receptor β1-AR subtype. Carvedilol has been observed to block the oscillatory intracellular calcium changes induced by α1D-AR and α1B-AR, and shown to have a higher oxidative effect than Atenolol. The S(-) enantiomer of Carvedilol acts as a β-blocker, and the R(+) and S (-) enantionmers both block the α1. Carvedilol is an inhibitor of α1B-AR, β1-AR, β2-AR and α1D-AR.


Suppliers

Aozeal Certified Standards (AOCS), Inc.
C0002.00
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI6902760
H&Z Industry Co.,Ltd
HIC200800
Shandong SanYoung Industry Co., Ltd
SSI3501400
Chemlyte Solutions
CS180540
Arevipharma GmbH
A160320
Inke S.A.
IS90270
Jai Radhe Sales
JRS150600
CellMark AB
CA110330
Xiamen Equation Chemical Co.,Ltd
XECC3201600
Sancai Industry Co.,Ltd.
SIC240960
Aecochem Corp.
AC140420
Sigma-Aldrich International GmbH
SI320960
scienTEST - bioKEMIX GmbH
S-B2501000
AK Scientific, Inc.
AS190570
Capot Chemical Co., Ltd.
18218
Leap Chem Co., Ltd
LC180540
Santa Cruz Biotechnology, Inc.
200157
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CAS equal suppliers

Carvedilol 
Jiwan Pharmaceutical Technology Co., Ltd.
JPT4921968

Prices & Availability




Data is processed


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Properties for Carvedilol

Molecular Weight:
406.47 g·mol−1
Density:
1.25 g/cm3 (Predicted)
Melting point:
113-117 °C
Boiling point:
655.22° C at 760 mmHg (Predicted)
Solubility:
Soluble in DMSO (>25 mg/ml), ethanol (10 mg/ml), methanol (33.8 mg/ml), phosphate buffer (pH 4) (0.43 mg/ml) at 37° C, water (partly miscible), chloroform, methylene chloride, and ethyl ether (slightly soluble). Insoluble in isopropanol.
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Safety & Transport Information

Risk Codes:
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
S61 - Avoid release to the environment. Refer to special instructions/safety data sheet
Hazard Classes:
irritant
Hazard Symbols:
N, Xn
Hazard symbol N Hazard symbol Xn
Storage temperature :
Store at +4 °C
RID/ADR certification :
UN 3077 9 / PG 3
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Alternative Distributors of [Carvedilol]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Inter-Chemical Ltd. | Ningbo Zhengrun Chemicals Co., Ltd. Exp. Dept. | Matrix Laboratories Limited | Argosi International Co., Ltd. | 3B Scientific Corporation | Hangzhou Think Chemical Co., Ltd. | Changsha Huajia Chemical Science Co., Ltd. | Molekula GmbH | SLN Pharmachem | Ningbo Highpharm Chem&Indu Co., Ltd. | Jinan Jinao Chemical Development Co., Ltd. | Xiang Ding Chemical International Co., Ltd | Qufu Hongly Chemical Industry CO., Ltd. | Qichun QiLong Chemical Co., Ltd. | Nantong Chem-Tech. (Group) Co., Ltd. | Pharmasi Chemicals Co., Ltd. | TCI Europe NV | China Yangzhou Wandong Medical Co., Ltd. | Matrix Scientific | Synfine Research Inc. | New Dragon Industrial Co., Ltd | G. Amphray Laboratories | Jinan Victory Imp. & Exp. Co., Ltd. | Hana Pharm. Co., Ltd. | Conier Chem & Pharma Ltd | ShangHai Biochempartner Co., Ltd. | Hangzhou Hysen Pharma Co., Ltd. | Formax Chemicals Co., Ltd. | Long Island Pharmaceutical & Chemical Co. Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd. | Shanghai AOKChem Group Limited | Suzhou Rovathin Pharmatech Co., Ltd | Shanghai Richem International Co., Ltd. | Abtonsmart Chemicals Co., Ltd. | Kinfon Pharmaceutical and Chemical Service Co., Ltd. | Qingdao Henley Co., Ltd. | Lanospharma Laboratories Co., Ltd. | Evershine Chemical Co.,Ltd. | TCS INDUSTRY LTD. | Jinan Great Chemical Co., Ltd. | Ningbo Hi-Tech Biochemicals Co., Ltd. | East Chemical Industry Co., Ltd. | Shanghai Witofly Chemical Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | API Vanguard | Hefei Photochem Trading Co., Ltd | King Tang Chemical Group Industry Co., Ltd. | Watson International Ltd | Hubei Yuancheng Saichuang Tech.Co.,Ltd | Cfm Oskar Tropitzsch GmbH | Aopharm | BOC Sciences | Jinan Rouse Industry Co., Ltd. | Jinan Haohua Industry Co., Ltd. | Suzhou Vosun Chemical Co.,Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Haihang Industry Co., Ltd. | Clearsynth Canada INC. | scienTEST

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