SU 5402 | CAS 215543-92-3 | Chemical-Suppliers

Element: 5402

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C-S » Chemicals » -PX71587

Identification

SU 5402

CAS:

215543-92-3

EINECS:

Molecular Formula:

C₁₇H₁₆N₂O₃

MDL:

SMILES:

CC1=CNC(C=C2/C(=O)NC3=CC=CC=C23)=C1CCC(O)=O

Synonym:

su-5402/su5402 ; su5402 ; 2-[(1,2-dihydro-2-oxo-3h-indol-3-ylidene)methyl]-4-methyl-1h-pyrrole-3-propanoic acid ; 3-[3-(2-carboxyethyl)-4-methylpyrrol-2-methylidenyl]-2-indolinone ; 2-[(1,2-dihydro-2-oxo-3h-indol-3-ylidene)methyl]-4-methyl- ; 3-[4-methyl-2-(2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-1h-pyrrol-3-yl]-propionic acid ; pnu-0290908 ; su 5402, >=98% ; 3-[4-methyl-2-[(2-oxo-1h-indol-3-ylidene)methyl]-1h-pyrrol-3-yl]propanoic acid ; pf-02969207

Description

SU 5402 is a fibroblast growth factor receptor (FGFR)-specific tyrosine kinase inhibitor. Multiple myeloma studies suggest that SU 5402 inhibits FGFR3 phosphorylation in vitro. Research shows that inhibition of FGFR results in the blocking of nodal vesicular parcels (NVPs) secretion and an increase of Ca2⁺. Additionally, SU 5402 has been observed to inhibit IL-1β-induced MAPK activity.

Suppliers

Aea.ltd

A4998

Hangzhou Ocean Chemical Co., Ltd.

HOC231924

BOC Sciences

BS84252

Amadis Chemical Company Limited

ACCL2171085

Santa Cruz Biotechnology, Inc.

204308

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CAS equal suppliers

SU5402

Hangzhou Ocean Chemical Co., Ltd.

HOC198792

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Chemieliva Pharmaceutical Co., Ltd.

CP210630

SU5402

Pharmacore Co., Limited

PL138414

SU-5402

Capot Chemical Co., Ltd.

22440

SU-5402

ShangHai Biochempartner Co., Ltd.

BCP01961

SU-5402

Excenen Pharmatech Co., Ltd.

EX-A2844

(Z)-3-(4-Methyl-2-((2-oxoindolin-3-ylidene)-methyl)-1H-pyrrol-3-yl)propanoic acid

Hangzhou MolCore BioPharmatech Co.,Ltd.

MC110927

2-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-4-methyl-1H-pyrrole-3-propanoic acid

Leap Chem Co., Ltd

LC1683050490

Prices & Availability

Data is processed

Properties for SU 5402

Molecular Weight:

296.32 g·mol−1

Melting point:

>222 °C (dec.)

Solubility:

Soluble to 100 mM in 1eq. NaOH and to 100 mM in DMSO

Safety & Transport Information

Storage temperature :

0-6°C

Alternative Distributors of [SU 5402]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

ShangHai Biochempartner Co., Ltd. | Shanghai Boyle Chemical Co., Ltd. | Suzhou Rovathin Pharmatech Co., Ltd | Xi´an Chemsoar Medical Technology Co., Ltd.

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